1-Methyl-4-[2-(2-naphthyl)ethenyl]pyridinium iodide

Discontinued Product

Unfortunately 1-Methyl-4-[2-(2-naphthyl)ethenyl]pyridinium iodide (Cat. No. 0559) has been withdrawn from sale for commercial reasons.
Cat.No. 0559 - 1-Methyl-4-[2-(2-naphthyl)ethenyl]pyridinium iodide
Description: Choline acetyl transferase inhibitor

Biological Activity

Inhibitor of choline acetyltransferase.

Technical Data

M. Wt 373.22
Storage Desiccate at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 373.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.68 mL 13.4 mL 26.79 mL
5 mM 0.54 mL 2.68 mL 5.36 mL
10 mM 0.27 mL 1.34 mL 2.68 mL
50 mM 0.05 mL 0.27 mL 0.54 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

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Product Datasheets

Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service.
Safety Datasheet


References are publications that support the products' biological activity.

Cavallito et al (1969) Choline acetyltransferase inhibitors. Configurational and electronic features of styrylpyridine analogs. J.Med.Chem. 12 134 PMID: 5763010

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Keywords: 1-Methyl-4-[2-(2-naphthyl)ethenyl]pyridinium iodide, supplier, Other, Acetylcholine, Non-selective, Muscarinics, Other, Acetylcholine, Tocris Bioscience

Citations for 1-Methyl-4-[2-(2-naphthyl)ethenyl]pyridinium iodide

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

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Updated in 2014, this review by Sue Wonnacott summarizes the diverse structure and function of nicotinic acetylcholine receptors and gives an in-depth review of the ligands available for nAChR research. Compounds available from Tocris are listed.


Pain Poster

Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.