1-Acetyl-4-methylpiperazine hydrochloride

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Cat.No. 0351 - 1-Acetyl-4-methylpiperazine hydrochloride | C7H14N2O.HCl | CAS No. 144205-68-5
Description: Nicotinic agonist

Biological Activity

Structural analog of acetylcholine that acts as a nAChR agonist.

Technical Data

M. Wt 178.66
Formula C7H14N2O.HCl
Storage Desiccate at RT
CAS Number 144205-68-5
PubChem ID 53411727
Smiles CC(N1CCN(C)CC1)=O.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 50 mM in water

Preparing Stock Solutions

The following data is based on the product molecular weight 178.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 5.6 mL 27.99 mL 55.97 mL
5 mM 1.12 mL 5.6 mL 11.19 mL
10 mM 0.56 mL 2.8 mL 5.6 mL
50 mM 0.11 mL 0.56 mL 1.12 mL

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Product Datasheets

Safety Datasheet


References are publications that support the products' biological activity.

Garcha et al (1993) Behavioural and ligand binding studies in rats with 1-acetyl-4-methylpiperazine a novel nicotinic agonist. Psychopharmacology 110 347 PMID: 7831430

Warpman et al (1998) Regulation of nicotinic receptor subtypes following chronic nicotinic agonist exposure in M10 and SH-SY5Y neuroblastoma cells. J.Neurochem. 70 2028 PMID: 9572289

If you know of a relevant reference for 1-Acetyl-4-methylpiperazine hydrochloride, please let us know.

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Citations for 1-Acetyl-4-methylpiperazine hydrochloride

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