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Submit ReviewInactive analog of forskolin (Cat. No. 1099); does not activate adenylyl cyclase.
M. Wt | 378.5 |
Formula | C22H34O5 |
Storage | Store at -20°C |
Purity | ≥98% (HPLC) |
CAS Number | 64657-18-7 |
PubChem ID | 10452268 |
InChI Key | ZKZMDXUDDJYAIB-OJPJTMFRSA-N |
Smiles | C=C[C@](C3)(C)O[C@]2(C)[C@@H](OC(C)=O)[C@@H](O)[C@@]1([H])C(C)(C)CCC[C@@](C)1C2C3=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Wadler and Wiernik (1988) Partial reversal of dox. resistance by forskolin and 1,9-dideoxyforskolin in murine sarcoma S180 variants. Cancer Res. 48 539 PMID: 2825978
McHugh and McGee (1986) Direct anesthetic-like effects of forskolin on the nicotinic acetylcholine receptors of PC12 cells. J.Biol.Chem. 261 3103 PMID: 3005280
Keywords: 1,9-Dideoxyforskolin, 1,9-Dideoxyforskolin supplier, inactive, analogs, analogues, forskolin, adenylyl, adenylate, cyclases, Adenylyl, Cyclase, 5034, Tocris Bioscience
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Schizophrenia is a debilitating psychiatric disorder that affects 1% of the worldwide population. This poster describes the neurobiology of Schizophrenia, as well as highlighting the genetic and environmental factors that play a fundamental role in the etiology of the disease. The current and emerging drug targets are also discussed.