Dihydrofolate Reductase Inhibitors

Cat. No. Product Name / Activity
1230 Methotrexate
Dihydrofolate reductase inhibitor
6185 Pemetrexed
High affinity dihydrofolate reductase inhibitor; also inhibits thymidylate synthase, GARFT and AICART
7362 Phototrexate
Photoswitchable inhibitor of human dihydrofolate reductase
3918 Pyrimethamine
DHFR inhibitor; also potent inhibitor of multidrug and toxin extrusion (MATE) transporters and STAT3 inhibitor
1592 SCH 79797 dihydrochloride
Inhibits DHFR; also potent and selective PAR1 antagonist; broad spectrum antibiotic