Cat. No. 2927
Chemical Name: N-Ethyl-5-methyl-2-(1-methylethyl)c
Biological ActivityCooling agent that is an agonist at TRPM8 receptors (EC50 = 3.7 μM).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Bodding (2007) TRP proteins and cancer. Cell Signal. 19 617. PMID: 17029734.
Rovner (2007) Better than mint. C&EN 85 95.
Behrendt et al (2004) Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay. Br.J.Pharmacol. 141 737. PMID: 14757700.
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Citations are publications that use Tocris products.
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Keywords: WS 3, supplier, TRPM8, agonists, cooling, agent, Channels, Transient, Receptor, Potential, WS3, Tocris Bioscience, TRPM Agonist products