Acetaminophen

Cat. No. 1706

Acetaminophen C8H9NO2 [103-90-2]

Price and Availability

For Acetaminophen pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Alternative Name: Paracetamol

Chemical Name: N-(4-Hydroxyphenyl)acetamide

Biological Activity

Cyclooxygenase inhibitor; may be selective for COX-3 (IC50 values are 460, > 1000 and > 1000 μM for canine COX-3, and murine COX-1 and COX-2 respectively). Widely used analgesic and antipyretic agent.

Technical Data

M.Wt:
151.16
Formula:
C8H9NO2
Solubility:
Soluble to 100 mM in ethanol and to 100 mM in DMSO
Purity:
>99 %
Storage:
Store at RT
CAS No:
103-90-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Chandrasekharan et al (2002) COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression. Proc.Natl.Acad.Sci.U.S.A. 99 13926. PMID: 12242329.

Chong et al (2001) Effect of acetaminophen on atherosclerosis. Ann.Pharmacother. 35 1476. PMID: 11724102.

Riendeau et al (1997) Comparison of the cyclooxygenase-1 inhibitory properties of nonsteroidal anti-inflammatory drugs (NSAIDS) and selective COX-2 inhibitors, using sensitive microsomal and platelet assays. Can.J.Physiol.Pharmacol. 75 1088. PMID: 9365818.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for Acetaminophen include:

Factor et al (2007) Adenosine regulation of alveolar fluid clearance. Proc Natl Acad Sci U S A 104 4083. PMID: 17360481.

Do you know of a great paper that uses Acetaminophen from Tocris? If so please let us know.

View Related Products by Target

View Related Products by Product Action

Keywords: Acetaminophen, supplier, Cyclooxygenase, inhibitors, inhibits, COX-3, Oxygenases, Oxidases, Tocris Bioscience, Cyclooxygenase Inhibitor products

Quick Order

Find multiple products by catalog number

divider line

Cancer Research Product Guide

Cancer Research Product Guide

Our Cancer Research Guide highlights over 750 products for cancer research. Request copy or view PDF today.

divider line

Immunology Guide

Immunology Product Listing

Our Immunology listing highlights over 190 products for immunology research. Request copy or view PDF today.

divider line

Pain Research Product Guide

Pain Research Product Guide

Our Pain guide highlights over 280 products for Pain research. Request copy or view PDF today.

divider line

New Therapies and Challenges in Asthma

Written by Peter J. Barnes

Asthma Life Science Poster

Our Asthma poster highlights key pathways and new therapies used to treat asthma, including those currently in clinical development. Request copy today.

divider line

Alzheimer's Disease: Neurobiology and Drug Targets

Written by Alan Palmer

Alzheimer's Life Science Poster

Our Alzheimer's disease poster summarizes the structural and functional changes observed in the progression of this neurodegenerative disease. Request copy or view PDF today.

divider line

Parkinson's disease: Neurobiology and Therapeutic Strategies

Written by Anthony H.V. Schapira

Parkinson's Life Science Poster

Our Parkinson's disease (PD) poster summarizes the neurobiology of the disease, and highlights current therapeutic treatments for symptomatic PD. Request copy or view PDF today.

divider line

New Products in this Area

PF 06281355

Selective myeloperoxidase (MPO) inhibitor

INCB 024360-analog

Potent indoleamine 2,3-dioxygenase (IDO) inhibitor

LM 10

Selective tryptophan 2,3-dioxygenase (TDO) inhibitor

NoxA1ds

Potent and selective NADPH oxidase 1 (NOX1) inhibitor

Sign-up for new product e-alerts
divider line

Twitter Updates

Follow @Tocris on Twitter

Follow us on Twitter!

Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.