FFN 102 mesylate
Cat. No. 5200
Chemical Name: 4-(2-Aminoethyl)-6-chloro-7-hydroxy
Biological ActivitypH responsive fluorescent false neurotransmitter (FFN). Selective dopamine transporter (DAT) and VMAT2 substrate. Exhibits no significant binding to a panel of 38 CNS receptors, including dopamine and serotonin receptors. Inhibits dopamine uptake.
Licensing InformationSold with the permission of Columbia University.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Rodriguez et al (2013) Fluorescent dopamine tracer resolves individual dopaminergic synapses and their activity in the brain. Proc.Natl.Acad.Sci.U.S.A. 110 870. PMID: 23277566.
Sames et al (2013) Visualizing neurotransmitter secretion at individual synapses. ACS Chem.Neurosci. 4 648. PMID: 23862751.
Lee et al (2010) Development of pH-responsive fluorescent false neurotransmitters. J.Am.Chem.Soc. 132 8828. PMID: 20540519.
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