Procaterol hydrochloride

Cat. No. 1102

Procaterol hydrochloride C16H22N2O3.HCl [62929-91-3]

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Chemical Name: (±)-erythro-8-Hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]carbostyril hydrochloride

Biological Activity

Specific and very potent β2 agonist.

Technical Data

Soluble to 100 mM in water and to 100 mM in DMSO
>99 %
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

Certificate of Analysis / Product Datasheet
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References are publications that support the products' biological activity.

Kotsonis and Majewski (1994) Facilitation by procaterol, a β-adrenoceptor agonist, of noradrenaline release in the pithed rat independently of angiotensin II formation. Br.J.Pharmacol. 113 781. PMID: 7858867.

Lakhlani et al (1994) Pharmacological characterization and anatomical localization of prejunctional β-adrenoceptors in the rat kidney. Br.J.Pharmacol. 111 1296. PMID: 8032617.

Yoshizaki et al (1977) Isomers of erythro-5-(1-hydroxy-2-isoproylaminobutyl)-8-hydroxycarbostyril, a new bronchodilator. J.Med.Chem. 20 1103. PMID: 894683.

Yoshizaki et al (1976) Sympathomimetic amines having a carbostyril nucleus. J.Med.Chem. 19 1138. PMID: 10441.

If you know of a relevant reference for Procaterol hydrochloride please let us know.

Citations are publications that use Tocris products. Selected citations for Procaterol hydrochloride include:

Copik et al (2015) Isoproterenol acts as a biased agonist of the α-1A-adrenoceptor that selectively activates the MAPK/ERK pathway. PLoS Med 10 e0115701. PMID: 25606852.

Rieg et al (2012) Cardiovascular agents affect the tone of pulmonary arteries and veins in precision-cut lung slices. PLoS One 6 e29698. PMID: 22216346.

Kaya et al (2009) Coupling of β2-adrenoceptors to XLαs and Gαs: a new insight into ligand-induced G protein activation. Front Cell Neurosci 329 350. PMID: 19144685.

Sivamani et al (2009) Stress-mediated increases in systemic and local epinephrine impair skin wound healing: potential new indication for β blockers. J Pharmacol Exp Ther 6 e12. PMID: 19143471.

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Keywords: Procaterol hydrochloride, supplier, Potent, α2-adrenoceptor, beta2-adrenoceptor, b2-adrenoceptor, β2-adrenergic, α2-adrenergic, beta2-adrenergic, b2-adrenergic, agonist, receptors, Tocris Bioscience, Adrenergic β2 Receptor Agonist products

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