Tyrphostin B44, (+) enantiomer
Cat. No. 0579
Chemical Name: (S)-(E)-2-Cyano-3-(3',4'-dihydroxyphe
Biological ActivityEpidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 0.86 μM). Slightly less active than the (-) enantiomer (Cat. No. 0578).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Gazit et al (1991) Tyrphostins. 2. Heterocyclic and α-substituted benzylidenemalononitrile tyrophostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases. J.Med.Chem. 34 1896. PMID: 1676428.
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Keywords: Tyrphostin B44, (+) enantiomer, supplier, EGFR, kinase, inhibitors, inhibits, Epidermal, Growth, Factor, Receptors, ErbB, Her, RTK, Receptor, Tyrosine, Kinases, RTKs, (+)-TyrphostinB44, Tocris Bioscience, EGFR Inhibitor products
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