TACA

Cat. No. 0181

TACA C4H7NO2 [38090-53-8]

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Chemical Name: trans-4-Aminocrotonic acid

Biological Activity

The trans-isomer of CACA. Potent GABAA agonist, GABA uptake inhibitor and substrate for GABA-T. Also GABAA-ρ agonist.

Technical Data

M.Wt:
101.1
Formula:
C4H7NO2
Solubility:
Soluble to 100 mM in water
Storage:
Store at RT
CAS No:
38090-53-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

Chebib et al (1997) Analogues of γ-aminobutyric acid (GABA) and trans-4-aminocrotonic acid (TACA) substituted in the 2 position as GABAC receptor antagonists. Br.J.Pharmacol. 122 1551. PMID: 9422798.

Johnston et al (1996) GABAC receptors: relatively simple transmitter-gated ion channels. TiPS 17 319. PMID: 8885697.

Johnston et al (1975) cis and trans-4-Aminocrotonic acid as GABA analogues of restricted conformation. J.Neurochem. 24 157. PMID: 234147.

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Keywords: TACA, supplier, GABAA, agonists, GABA-T, GABA, uptake, inhibitors, inhibits, GABAC, Receptors, BGT-1, GAT, Transporters, Monoamine, Neurotransmitter, Tocris Bioscience, GABAA Receptor Agonist products

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