Tocrifluor T1117

Cat. No. 2540

Tocrifluor T1117 C56H53Cl2N7O5 [1186195-59-4]

Price and Availability

For Tocrifluor T1117 pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: N-(Piperidin-1-yl)-5-(4-(4-(3-(5-carboxamidotetramethylrhodaminyl)propyl))phenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide

Biological Activity

Fluorescent form of AM 251 (Cat. No. 1117). AM 251 conjugated with 5-carboxytetramethylrhodamine (5-TAMRA) that fluoresces at 543 nm excitation (590 nm emission). Displays GPR55 binding activity.

Technical Data

M.Wt:
974.97
Formula:
C56H53Cl2N7O5
Solubility:
Soluble to 10 mM in DMSO
Purity:
>95 %
Storage:
Store at -20°C
CAS No:
1186195-59-4

Resources

Other Information

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

Certificate of Analysis / Product Datasheet
Select another batch:

References are publications that support the products' biological activity.

Bruno et al (2014) Beyond radio-displacement techniques for identification of CB1 ligands: the first application of a fluorescence-quenching assay. Sci.Rep. 4 3757. PMID: 24441508.

Sylantyev et al (2013) Cannabinoid- and lysophosphatidylinositol-sensitive receptor GPR55 boosts neurotransmitter release at central synapses. Proc.Natl.Acad.Sci.U.S.A. 110 5193. PMID: 23472002.

Daly et al (2010) Fluorescent ligand binding reveals heterogeneous distribution of adrenoceptors and 'cannabinoid-like' receptors in small arteries. Br.J.Pharmacol. 159 787. PMID: 20136833.

Daly et al (2008) Visualisation of vascular cannabinoid receptors and their potential interaction with α1-adrenergic receptors. Vascular and Smooth Muscle Phys.Soc. Symposium.

If you know of a relevant reference for Tocrifluor T1117 please let us know.

Citations are publications that use Tocris products. Selected citations for Tocrifluor T1117 include:

Tortoriello et al (2013) Targeted lipidomics in Drosophila melanogaster identifies novel 2-monoacylglycerols and N-acyl amides. PLoS One 8 e67865. PMID: 23874457.

Daly et al (2010) Fluorescent ligand binding reveals heterogeneous distribution of adrenoceptors and 'cannabinoid-like' receptors in small arteries. Br J Pharmacol 159 787. PMID: 20136833.

Do you know of a great paper that uses Tocrifluor T1117 from Tocris? If so please let us know.

View Related Products by Product Action

Keywords: Tocrifluor T1117, supplier, fluorescent, CB1, receptor, ligands, Fluorescent, Probes, cannabinoids, Receptors, cb1r, cb2r, Tocris Bioscience, Fluorescent Probe products

Quick Order

Find multiple products by catalog number

divider line

New Product Guide

Spring/Summer 2017

New Product Guide (Spring/Summer 2017)

Our New Product guide highlights over 130 new products added in the first half of 2017. View PDF today.

divider line

New Products in this Area

PA Janelia Fluor® 646, SE

Photoactivatable cell permeable fluorescent dye; supplied as NHS ester

PA Janelia Fluor® 549, SE

Photoactivatable cell permeable fluorescent dye; supplied as NHS ester

Cyanine 7, SE

Near-infrared fluorescent dye for labeling of amines

Cyanine 3, SE

Orange fluorescent dye for labeling of amines

FFN 200 dihydrochloride

Selective fluorescent VMAT2 substrate

Janelia Fluor® 646, SE

Cell permeable fluorescent dye; supplied as NHS ester

Janelia Fluor® 549, SE

Cell permeable fluorescent dye; supplied as NHS ester

Sign-up for new product e-alerts
divider line

LinkedIn Updates

Follow Tocris on LinkedIn

Follow us on LinkedIn!

Visit our LinkedIn page for the latest Tocris news, events and updates.