Cat. No. 0794
Chemical Name: 2-(3,4-Dichlorophenyl)-N-methyl-N-[
Biological ActivityAn irreversible and selective antagonist at the κ receptor, with persistent effect in vivo.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Chang et al (1994) 2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-(3-isothiocyanatophenyl)-2-(1-pyrrolidinyl)ethyl]acetamide: an opioid receptor affinity label that produces selective and long lasting κ antagonism in mice. J.Med.Chem. 37 1547. PMID: 8201586.
Chang et al (1994) κ opioid receptor selective affinity labels: Electrophilic benzeneacetamides as κ-selective opioid antagonists. J.Med.Chem. 37 4490. PMID: 7799399.
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Citations are publications that use Tocris products. Selected citations for DIPPA hydrochloride include:
Jones et al (2010) Identification of a κ-opioid agonist as a potent and selective lead for drug development against human African trypanosomiasis. Biochem Pharmacol 80 1478. PMID: 20696141.
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Keywords: DIPPA hydrochloride, supplier, Selective, irreversible, κ-opioid, kappa-opioid, antagonists, KOP, Receptors, OP2, Tocris Bioscience, κ Opioid Receptor Antagonist products
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