Translocation of proteins occurs either during translation (co-translational translocation) or after translation (post-translational translocation) and depends on the N'-terminal signal-recognition particle (SRP). The SRP interacts with a SRP receptor on the ER and promotes transport of proteins into the ER lumen where they are prepared for secretion.

Literature (1)
Cat. No. Product Name / Activity
1231 Brefeldin A
Disrupts protein translocation to Golgi
4417 DBeQ
Selective and reversible p97 ATPase inhibitor
5172 FLI 06
Inhibitor of Notch signaling
3584 Golgicide A
Arrests secretion of soluble and membrane-associated proteins
1987 Leptomycin B
Inhibits nuclear export of proteins; antitumor
5153 ML 240
ATP-competitive inhibitor of p97 ATPase
6180 NMS 873
Potent and selective p97 ATPase (VCP) allosteric inhibitor

Literature for Translocation

Tocris offers the following scientific literature for Translocation to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

New Product Guide

New Product Guide [Spring/Summer 2019]

Our new product guide highlights over 215 new products added to the Tocris Bioscience range during the first half of 2019.

  • 7-TM Receptors
  • Enzymes
  • Enzyme-Linked Receptors
  • Ion Channels
  • Nuclear Receptors
  • Transporters
  • Chemogenetics
  • Epigenetics
  • Fluorescent Imaging
  • Signal Transduction
  • Stem Cells