ZM 226600

Pricing Availability Delivery Time Qty
Cat.No. 0882 - ZM 226600 | C16H14F3NO4S | CAS No. 147695-92-9
Description: Kir6 (KATP) channel opener
Chemical Name: N-(4-Phenylsulfonylphenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide
Datasheet
Citations
Literature

Biological Activity

Potent Kir6 (KATP) channel opener (EC50 = 0.5 μM), devoid of antiandrogen properties.

Licensing Information

Sold with the permission of AstraZeneca UK Ltd.

Technical Data

M. Wt 373.35
Formula C16H14F3NO4S
Storage Store at RT
CAS Number 147695-92-9
PubChem ID 5240098
InChI Key LJLXQHHFAKVTNP-UHFFFAOYSA-N
Smiles CC(O)(C(=O)NC1=CC=C(C=C1)S(=O)(=O)C1=CC=CC=C1)C(F)(F)F

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 37.34 100

Preparing Stock Solutions

The following data is based on the product molecular weight 373.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.68 mL 13.39 mL 26.78 mL
5 mM 0.54 mL 2.68 mL 5.36 mL
10 mM 0.27 mL 1.34 mL 2.68 mL
50 mM 0.05 mL 0.27 mL 0.54 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Grant et al (1994) Anilide tertiary carbinols: a novel series of K+ channel openers. TiPS 15 402 PMID: 7855900


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View Related Products by Product Action

View all Inward Rectifier Potassium (Kir) Channel Activators

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Citations for ZM 226600

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