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Submit ReviewZM 226600 is a potent Kir6 (KATP) channel opener (EC50 = 0.5 μM), devoid of antiandrogen properties.
Sold with the permission of AstraZeneca UK Ltd.
M. Wt | 373.35 |
Formula | C16H14F3NO4S |
Storage | Store at RT |
CAS Number | 147695-92-9 |
PubChem ID | 5240098 |
InChI Key | LJLXQHHFAKVTNP-UHFFFAOYSA-N |
Smiles | CC(O)(C(=O)NC1=CC=C(C=C1)S(=O)(=O)C1=CC=CC=C1)C(F)(F)F |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solvent | Max Conc. mg/mL | Max Conc. mM | |
---|---|---|---|
Solubility | |||
DMSO | 37.34 | 100 |
The following data is based on the product molecular weight 373.35. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 2.68 mL | 13.39 mL | 26.78 mL |
5 mM | 0.54 mL | 2.68 mL | 5.36 mL |
10 mM | 0.27 mL | 1.34 mL | 2.68 mL |
50 mM | 0.05 mL | 0.27 mL | 0.54 mL |
References are publications that support the biological activity of the product.
Grant et al (1994) Anilide tertiary carbinols: a novel series of K+ channel openers. TiPS 15 402 PMID: 7855900
If you know of a relevant reference for ZM 226600, please let us know.
View all Inward Rectifier Potassium (Kir) Channel Activators
Keywords: ZM 226600, ZM 226600 supplier, KATP, openers, Potassium, KIR, Channels, Inward, Rectifier, K+, ZM226600, AstraZeneca, Kir6, rectifier, 0882, Tocris Bioscience
Citations are publications that use Tocris products.
Currently there are no citations for ZM 226600. Do you know of a great paper that uses ZM 226600 from Tocris? Please let us know.
Average Rating: 5 (Based on 1 Review.)
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