ZM 226600

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Cat.No. 0882 - ZM 226600 | C16H14F3NO4S | CAS No. 147695-92-9
Description: Kir6 (KATP) channel opener
Chemical Name: N-(4-Phenylsulfonylphenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide
Reviews (1)
Literature (3)

Biological Activity for ZM 226600

ZM 226600 is a potent Kir6 (KATP) channel opener (EC50 = 0.5 μM), devoid of antiandrogen properties.

Licensing Information

Sold with the permission of AstraZeneca UK Ltd.

Technical Data for ZM 226600

M. Wt 373.35
Formula C16H14F3NO4S
Storage Store at RT
CAS Number 147695-92-9
PubChem ID 5240098
Smiles CC(O)(C(=O)NC1=CC=C(C=C1)S(=O)(=O)C1=CC=CC=C1)C(F)(F)F

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for ZM 226600

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 37.34 100

Preparing Stock Solutions for ZM 226600

The following data is based on the product molecular weight 373.35. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.68 mL 13.39 mL 26.78 mL
5 mM 0.54 mL 2.68 mL 5.36 mL
10 mM 0.27 mL 1.34 mL 2.68 mL
50 mM 0.05 mL 0.27 mL 0.54 mL

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References for ZM 226600

References are publications that support the biological activity of the product.

Grant et al (1994) Anilide tertiary carbinols: a novel series of K+ channel openers. TiPS 15 402 PMID: 7855900

If you know of a relevant reference for ZM 226600, please let us know.

View Related Products by Product Action

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Keywords: ZM 226600, ZM 226600 supplier, KATP, openers, Potassium, KIR, Channels, Inward, Rectifier, K+, ZM226600, AstraZeneca, Kir6, rectifier, 0882, Tocris Bioscience

Citations for ZM 226600

Citations are publications that use Tocris products.

Currently there are no citations for ZM 226600. Do you know of a great paper that uses ZM 226600 from Tocris? Please let us know.

Reviews for ZM 226600

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ZM 226600 was used to assess Kir2.2 channel opening.
By Anonymous on 11/29/2018
Assay Type: In Vitro
Species: Human

ZM 226600 was used to assess Kir2.2 channel opening.

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Literature in this Area

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