ZM 226600
Biological Activity
Potent Kir6 (KATP) channel opener (EC50 = 0.5 μM), devoid of antiandrogen properties.
Licensing Information
Sold with the permission of AstraZeneca UK Ltd.
Technical Data
| M. Wt | 373.35 |
| Formula | C16H14F3NO4S |
| Storage | Store at RT |
| CAS Number | 147695-92-9 |
| PubChem ID | 5240098 |
| InChI Key | LJLXQHHFAKVTNP-UHFFFAOYSA-N |
| Smiles | CC(O)(C(=O)NC1=CC=C(C=C1)S(=O)(=O)C1=CC=CC=C1)C(F)(F)F |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 37.34 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 373.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.68 mL | 13.39 mL | 26.78 mL |
| 5 mM | 0.54 mL | 2.68 mL | 5.36 mL |
| 10 mM | 0.27 mL | 1.34 mL | 2.68 mL |
| 50 mM | 0.05 mL | 0.27 mL | 0.54 mL |
Molarity Calculator
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Dilution Calculator
Product Datasheets
References
References are publications that support the products' biological activity.
Grant et al (1994) Anilide tertiary carbinols: a novel series of K+ channel openers. TiPS 15 402 PMID: 7855900
If you know of a relevant reference for ZM 226600, please let us know.
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Keywords: KATP openers Potassium KIR Channels Inward Rectifier K+ ZM226600 AstraZeneca Kir6 Inward rectifier Potassium Channels
Citations for ZM 226600
Citations are publications that use Tocris products.
Currently there are no citations for ZM 226600. Do you know of a great paper that uses ZM 226600 from Tocris? If so please let us know.
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