ZM 226600

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Cat.No. 0882 - ZM 226600 | C16H14F3NO4S | CAS No. 147695-92-9
Description: Kir6 (KATP) channel opener
Chemical Name: N-(4-Phenylsulfonylphenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide
Datasheet
Citations
Reviews (1)
Literature (3)

Biological Activity

Potent Kir6 (KATP) channel opener (EC50 = 0.5 μM), devoid of antiandrogen properties.

Licensing Information

Sold with the permission of AstraZeneca UK Ltd.

Technical Data

M. Wt 373.35
Formula C16H14F3NO4S
Storage Store at RT
CAS Number 147695-92-9
PubChem ID 5240098
InChI Key LJLXQHHFAKVTNP-UHFFFAOYSA-N
Smiles CC(O)(C(=O)NC1=CC=C(C=C1)S(=O)(=O)C1=CC=CC=C1)C(F)(F)F

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 37.34 100

Preparing Stock Solutions

The following data is based on the product molecular weight 373.35. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.68 mL 13.39 mL 26.78 mL
5 mM 0.54 mL 2.68 mL 5.36 mL
10 mM 0.27 mL 1.34 mL 2.68 mL
50 mM 0.05 mL 0.27 mL 0.54 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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References

References are publications that support the biological activity of the product.

Grant et al (1994) Anilide tertiary carbinols: a novel series of K+ channel openers. TiPS 15 402 PMID: 7855900


If you know of a relevant reference for ZM 226600, please let us know.

View Related Products by Product Action

View all Inward Rectifier Potassium (Kir) Channel Activators

Keywords: ZM 226600, ZM 226600 supplier, KATP, openers, Potassium, KIR, Channels, Inward, Rectifier, K+, ZM226600, AstraZeneca, Kir6, rectifier, 0882, Tocris Bioscience

Citations for ZM 226600

Citations are publications that use Tocris products.

Currently there are no citations for ZM 226600. Do you know of a great paper that uses ZM 226600 from Tocris? Please let us know.

Reviews for ZM 226600

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ZM 226600 was used to assess Kir2.2 channel opening.
By Anonymous on 11/29/2018
Assay Type: In Vitro
Species: Human

ZM 226600 was used to assess Kir2.2 channel opening.

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