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ZIP (Scrambled)

Cat. No. 3215 3 Citations Submit a Review Datasheet / COA / SDS
Pricing Availability Delivery Time Qty
Cat.No. 3215 - ZIP (Scrambled) | Myr-Arg-Leu-Tyr-Arg-Lys-Arg-Ile-Trp-Arg-Ser-Ala-Gly-Arg | CAS No. 908012-18-0
Description: Control peptide for ZIP (Cat. No. 2549)
Alternative Names: z-Pseudosubstrate inhibitory peptide (scrambled)
Datasheet
Citations (3)
Reviews
Literature
Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity

Scrambled control peptide for ZIP.

Active Analog also available.

Technical Data

M. Wt 1928.4
Formula C90H154N30O17
Sequence RLYRKRIWRSAGR

(Modifications: Arg-1 = Myr-Arg)
Storage Desiccate at -20°C
CAS Number 908012-18-0
PubChem ID 90488814
InChI Key RGEXADZIYANTGH-HOHDCHNJSA-N
Smiles [H]N([C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(=O)CCCCCCCCCCCCC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solubility Soluble to 1 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 1928.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.52 mL 2.59 mL 5.19 mL
5 mM 0.1 mL 0.52 mL 1.04 mL
10 mM 0.05 mL 0.26 mL 0.52 mL
50 mM 0.01 mL 0.05 mL 0.1 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the biological activity of the product.

Krotova et al (2006) Peptides modified by myristoylation activate eNOS in endothelial cells through Akt phosphorylation. Br.J.Pharmacol. 148 732 PMID: 16715118

If you know of a relevant reference for ZIP (Scrambled), please let us know.

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Keywords: ZIP (Scrambled), ZIP (Scrambled) supplier, Control, peptide, ZIP, PKC, Protein, Kinases, C, z-Pseudosubstrate, inhibitory, (scrambled), Kinase, 3215, Tocris Bioscience

3 Citations for ZIP (Scrambled)

Citations are publications that use Tocris products. Selected citations for ZIP (Scrambled) include:

Laferriàre et al (2011) PKMζ is essential for spinal plasticity underlying the maintenance of persistent pain. Elife 7 99 PMID: 22185613

He et al (2011) PKMζ maintains drug reward and aversion memory in the basolateral amygdala and extinction memory in the infralimbic cortex. Neuropsychopharmacology 36 1972 PMID: 21633338

Li et al (2011) Inhibition of PKMzeta in nucleus accumbens core abolishes long-term drug reward memory. J Neurosci 31 5436 PMID: 21471379

Do you know of a great paper that uses ZIP (Scrambled) from Tocris? Please let us know.

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Literature in this Area

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