Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
5-HT re-uptake inhibitor; selective over noradrenalin and dopamine uptake (IC50 values are 0.33, 8.2 and 12 μM respectively). Modulates nociception and induces hyperglycemia in vivo, and is an orally active antidepressant.
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Ogren et al (1981) The pharmacology of zimelidine: a 5-HT selective reuptake inhibitor. Acta Psychiatr.Scand.Suppl. 290 127 PMID: 6452789
Fasmer et al (1987) Changes in nociception after acute and chronic administration of zimelidine: different effects in the formalin test and substance P behavioural assay. Neuropharmacology 26 309 PMID: 2438584
Sugimoto et al (1999) Involvement of serotonin in zimelidine-induced hyperglycemia in mice. Biol.Pharm.Bull. 22 1240 PMID: 10598036
Keywords: Zimelidine dihydrochloride, Zimelidine dihydrochloride supplier, Selective, 5-HT, reuptake, inhibitors, inhibits, Serotonin, Transporters, SERT, 5-Hydroxytryptamine, Monoamine, Neurotransmitter, 1767, Tocris Bioscience
Citations are publications that use Tocris products. Selected citations for Zimelidine dihydrochloride include:
Kim et al (2009) A novel flow cytometric high throughput assay for a systematic study on molecular mechanisms underlying T cell receptor-mediated integrin activation. PLoS One 4 e6044 PMID: 19557182
There are currently no reviews for this product. Be the first to review Zimelidine dihydrochloride and earn rewards!
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.