You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
ZAP 180013 New
Zeta-chain-associated protein kinase 70 (Zap70) inhibitor (IC50 = 1.8 μM in fluorescence polarization assay). Inhibits the interaction of Zap70 SH2 domain with immunoreceptor tyrosine-based activation motif (ITAMs), within the T-cell antigen receptor (TCR) signaling pathway.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 454.32. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.2 mL||11.01 mL||22.01 mL|
|5 mM||0.44 mL||2.2 mL||4.4 mL|
|10 mM||0.22 mL||1.1 mL||2.2 mL|
|50 mM||0.04 mL||0.22 mL||0.44 mL|
References are publications that support the biological activity of the product.
Visperas et al (2017) Identification of inhibitors of the association of ZAP-70 with the T-cell receptor by high-throughput screen. SLAS.Discov. 22 324 PMID: 27932698
If you know of a relevant reference for ZAP 180013, please let us know.
View Related Products by Product Action
Keywords: ZAP 180013, ZAP 180013 supplier, ZAP180013, zap70, zap-70, zeta, chain, associated, protein, kinase, 70, inhibitors, inhibits, immunoreceptor, tyrosine, activation, motif, t-cell, antigen, receptor, ITAMs, Other, RTKs, 6821, Tocris Bioscience
Citations for ZAP 180013
Citations are publications that use Tocris products.
Currently there are no citations for ZAP 180013. Do you know of a great paper that uses ZAP 180013 from Tocris? Please let us know.
Reviews for ZAP 180013
There are currently no reviews for this product. Be the first to review ZAP 180013 and earn rewards!
Have you used ZAP 180013?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.