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Discontinued ProductZ-YVAD-FMK (Cat. No. 2164) has been withdrawn from sale for commercial reasons.
Inhibitor of caspase-1 (ICE); inhibits apoptosis.
(Modifications: Tyr-1 = Z-Tyr, Asp-4 = (OMe)-fluoromethylketone)
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Avivi-Green et al (2002) Different molecular events account for butyrate-induced apoptosis in two human colon cancer cell lines. J.Nutr. 132 1812 PMID: 12097652
Ming et al (2002) Caspase-1 expression in multiple sclerosis plaques and cultured glial cells. J.Neurol.Sci. 197 9 PMID: 11997061
Winter et al (2004) Caspase-1 enhances the apoptotic response of prostate cancer cells to ionizing radiation. Anticancer Res. 24 1377 PMID: 15274298
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Keywords: Z-YVAD-FMK, Z-YVAD-FMK supplier, Caspase-1, ICE, inhibitors, inhibits, Caspases, Proteinases, Proteases, 2164, Tocris Bioscience
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Huntington's Disease Poster
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Programmed Cell Death Poster
There are two currently recognized forms of programmed cell death: apoptosis and necroptosis. This poster summarizes the signaling pathways involved in apoptosis, necroptosis and cell survival following death receptor activation, and highlights the influence of the molecular switch, cFLIP, on cell fate.