Discontinued ProductUnfortunately Z-YVAD-FMK (Cat. No. 2164) has been withdrawn from sale for commercial reasons.
Inhibitor of caspase-1 (ICE); inhibits apoptosis.
(Modifications: Tyr-1 = Z-Tyr, Asp-4 = (OMe)-fluoromethylketone)
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Preparing Stock Solutions
The following data is based on the product molecular weight 630.67. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.59 mL||7.93 mL||15.86 mL|
|5 mM||0.32 mL||1.59 mL||3.17 mL|
|10 mM||0.16 mL||0.79 mL||1.59 mL|
|50 mM||0.03 mL||0.16 mL||0.32 mL|
References are publications that support the products' biological activity.
Avivi-Green et al (2002) Different molecular events account for butyrate-induced apoptosis in two human colon cancer cell lines. J.Nutr. 132 1812 PMID: 12097652
Ming et al (2002) Caspase-1 expression in multiple sclerosis plaques and cultured glial cells. J.Neurol.Sci. 197 9 PMID: 11997061
Winter et al (2004) Caspase-1 enhances the apoptotic response of prostate cancer cells to ionizing radiation. Anticancer Res. 24 1377 PMID: 15274298
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Keywords: Z-YVAD-FMK, supplier, Caspase-1, ICE, inhibitors, inhibits, Caspases, Proteinases, Proteases, Caspases, Caspases, Tocris Bioscience
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