VUF 11207 fumarate

Discontinued Product

VUF 11207 fumarate (Cat. No. 4780) has been withdrawn from sale for commercial reasons.
Description: Potent ACKR3 (CXCR7) agonist
Chemical Name: N-[(2E)-3-(2-Fluorophenyl)-2-methyl-2-propen-1-yl]-3,4,5-trimethoxy-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]benzamide fumarate
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature (1)

Biological Activity for VUF 11207 fumarate

VUF 11207 fumarate is a potent ACKR3 (CXCR7) chemokine receptor agonist (EC50 = 1.6 nM). Induces recruitment of β-arrestin to CXCR7 in HEK293-CXCR7 cells.

Compound Libraries for VUF 11207 fumarate

VUF 11207 fumarate is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data for VUF 11207 fumarate

M. Wt 586.65
Formula C27H35FN2O4.C4H4O4
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 1785665-61-3
PubChem ID 90488970
InChI Key MTPOECCHJLVVGO-FDULSSLPSA-N
Smiles C\C(CN(CCC2N(C)CCC2)C(C3=CC(OC)=C(OC)C(OC)=C3)=O)=C/C1=C(F)C=CC=C1.OC(/C=C/C(O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for VUF 11207 fumarate

References for VUF 11207 fumarate

References are publications that support the biological activity of the product.

Wijtmans et al (2012) Synthesis, modeling and functional activity of substituted styrene-amides as small-molecule CXCR7 agonists. Eur.J.Med.Chem. 51 184 PMID: 22424612

View Related Products by Target

View Related Products by Product Action

View all Chemokine CXC Receptor Agonists

Keywords: VUF 11207 fumarate, VUF 11207 fumarate supplier, VUF11207, fumarate, CXCR7, chemokine, receptors, potent, agonist, Chemokine, CXC, Receptors, 4780, Tocris Bioscience

Citations for VUF 11207 fumarate

Citations are publications that use Tocris products.

Currently there are no citations for VUF 11207 fumarate.

Reviews for VUF 11207 fumarate

There are currently no reviews for this product. Be the first to review VUF 11207 fumarate and earn rewards!

Have you used VUF 11207 fumarate?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Rheumatoid Arthritis Poster

Rheumatoid Arthritis Poster

Rheumatoid arthritis (RA) is a chronic destructive inflammatory autoimmune disease that results from a breakdown in immune tolerance, for reasons that are as yet unknown. This poster summarizes the pathology of RA and the inflammatory processes involved, as well as describing some of the epigenetic modifications associated with the disease and the potential for targeting these changes in the discovery of new treatments.