Prohormone of calcitriol (Cat. No. 2551). Major circulating form of vitamin D. Suppresses PTH synthesis and secretion in bovine parathyroid cells (ED50 = 2 nM).
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble in DMSO and in ethanol|
References are publications that support the biological activity of the product.
Ritter et al (2006) 25-hydroxyvitamin D3 suppresses PTH synthesis and secretion by bovine parathyroid cells. Kidney Int. 70 654 PMID: 16807549
Rowling et al (2006) Megalin-mediated endocytosis of vitamin D binding protein correlates with 25-hydroxycholecalciferol actions in human mammary cells. J.Nutr. 136 2754 PMID: 17056796
Fedirko et al (2010) Blood 25-hydroxyvitamin D3 concentrations and incident sporadic colorectal adenoma risk: a pooled case-control study. Am.J.Epidemiol. 172 489 PMID: 20650953
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Keywords: Calcifediol, Calcifediol supplier, major, circulating, forms, vitamin, D, cholecalciferol, 25-HydroxyvitaminD3, calcitriol, 1,25-DihydroxyvitaminD3, 25-Hydroxyvitamin, D3, Calcidiol, Vitamin, Receptors, 4036, Tocris Bioscience
1 Citation for Calcifediol
Citations are publications that use Tocris products. Selected citations for Calcifediol include:
Kim et al (2014) Vitamin D Inhibits Expression and Activity of Matrix Metalloproteinase in Human Lung Fibroblasts (HFL-1) Cells. Biochim Biophys Acta 77 73 PMID: 25237378
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