Discontinued ProductUnfortunately Viloxazine hydrochloride (Cat. No. 0828) has been withdrawn from sale for commercial reasons.
Clinically used antidepressant. Inhibits noradrenaline and 5-HT uptake, and potentiates 5-HT-mediated effects in vitro and in vivo.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Preparing Stock Solutions
The following data is based on the product molecular weight 273.76. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.65 mL||18.26 mL||36.53 mL|
|5 mM||0.73 mL||3.65 mL||7.31 mL|
|10 mM||0.37 mL||1.83 mL||3.65 mL|
|50 mM||0.07 mL||0.37 mL||0.73 mL|
References are publications that support the products' biological activity.
Greenwood et al (1982) Stereospecificity of behavioural effects of viloxazine in bulbectomized rats does not correlate with its 5-HT-releasing action in vitro. J.Pharm.Pharmacol. 34 38 PMID: 6174722
Lippman and Pugsley (1976) Effects of viloxazine, an antidepressant agent, on biogenic amine uptake mechanisms and related activities. Can.J.Physiol.Pharmacol. 54 494 PMID: 974878
Martinez et al (1986) Inhibition of monamine oxidase by viloxazine in rats. Arzneimittelforschung 36 800 PMID: 2425816
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Keywords: Viloxazine hydrochloride, supplier, ICI, 58,834, Miscellaneous, Compounds, Miscellaneous, Compounds, Tocris Bioscience
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