Viloxazine hydrochloride

Discontinued Product

Viloxazine hydrochloride (Cat. No. 0828) has been withdrawn from sale for commercial reasons.
Cat.No. 0828 - Viloxazine hydrochloride | CAS No. 35604-67-2
Description: Antidepressant
Alternative Names: ICI 58,834
Chemical Name: 2-[(Ethoxyphenoxy)methyl)tetrahydro-1,4-oxazine hydrochloride
Literature (1)

Biological Activity

Clinically used antidepressant. Inhibits noradrenaline and 5-HT uptake, and potentiates 5-HT-mediated effects in vitro and in vivo.

Technical Data

M. Wt 273.76
Storage Store at RT
CAS Number 35604-67-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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References are publications that support the biological activity of the product.

Greenwood et al (1982) Stereospecificity of behavioural effects of viloxazine in bulbectomized rats does not correlate with its 5-HT-releasing action in vitro. J.Pharm.Pharmacol. 34 38 PMID: 6174722

Lippman and Pugsley (1976) Effects of viloxazine, an antidepressant agent, on biogenic amine uptake mechanisms and related activities. Can.J.Physiol.Pharmacol. 54 494 PMID: 974878

Martinez et al (1986) Inhibition of monamine oxidase by viloxazine in rats. Arzneimittelforschung 36 800 PMID: 2425816

Merck Index 12 10116

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Keywords: Viloxazine hydrochloride, Viloxazine hydrochloride supplier, ICI, 58,834, Miscellaneous, Compounds, 0828, Tocris Bioscience

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