Viloxazine hydrochloride

Discontinued Product

Unfortunately Viloxazine hydrochloride (Cat. No. 0828) has been withdrawn from sale for commercial reasons.
Cat.No. 0828 - Viloxazine hydrochloride | CAS No. 35604-67-2
Description: Antidepressant
Alternative Names: ICI 58,834
Chemical Name: 2-[(Ethoxyphenoxy)methyl)tetrahydro-1,4-oxazine hydrochloride

Biological Activity

Clinically used antidepressant. Inhibits noradrenaline and 5-HT uptake, and potentiates 5-HT-mediated effects in vitro and in vivo.

Technical Data

M. Wt 273.76
Storage Store at RT
CAS Number 35604-67-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 273.76. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.65 mL 18.26 mL 36.53 mL
5 mM 0.73 mL 3.65 mL 7.31 mL
10 mM 0.37 mL 1.83 mL 3.65 mL
50 mM 0.07 mL 0.37 mL 0.73 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Product Datasheets

Certificate of Analysis is currently unavailable
on-line. Please contact Customer Service
Safety Datasheet


References are publications that support the products' biological activity.

Greenwood et al (1982) Stereospecificity of behavioural effects of viloxazine in bulbectomized rats does not correlate with its 5-HT-releasing action in vitro. J.Pharm.Pharmacol. 34 38 PMID: 6174722

Lippman and Pugsley (1976) Effects of viloxazine, an antidepressant agent, on biogenic amine uptake mechanisms and related activities. Can.J.Physiol.Pharmacol. 54 494 PMID: 974878

Martinez et al (1986) Inhibition of monamine oxidase by viloxazine in rats. Arzneimittelforschung 36 800 PMID: 2425816

Merck Index 12 10116 PMID:

View Related Products by Target

Keywords: Viloxazine hydrochloride, supplier, ICI, 58,834, Miscellaneous, Compounds, Miscellaneous, Compounds, Tocris Bioscience

Citations for Viloxazine hydrochloride

Citations are publications that use Tocris products.

Currently there are no citations for Viloxazine hydrochloride.

Reviews for Viloxazine hydrochloride

There are currently no reviews for this product. Be the first to review Viloxazine hydrochloride and earn rewards!

Have you used Viloxazine hydrochloride?

Submit a review and receive an Amazon gift card.

$10US/$10CAN/€7/£6 gift card for a review without an image

$25US/$25CAN/€18/£15 gift card for a review with an image

*Offer only valid in the USA / Canada, UK and Europe

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

New Product Guide

New Product Guide (Spring/Summer 2017)

Our new product guide highlights over 130 new products added to the Tocris Bioscience range during the first half of 2017.

  • 7-TM Receptors
  • Enzymes
  • Enzyme-Linked Receptors
  • Ion Channels
  • Nuclear Receptors
  • Transporters
  • Apoptosis
  • Cell Metabolism
  • Epigenetics
  • Fluorescent Imaging
  • Signal Transduction
  • Stem Cells