Selective poly(ADP-ribose) polymerase (PARP) 2 inhibitor (IC50 values are 0.3 and 8.0 μM for PARP-2 and PARP-1 respectively).
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 279.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.58 mL||17.9 mL||35.81 mL|
|5 mM||0.72 mL||3.58 mL||7.16 mL|
|10 mM||0.36 mL||1.79 mL||3.58 mL|
|50 mM||0.07 mL||0.36 mL||0.72 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Moroni et al (2009) Selective PARP-2 inhibitors increase apoptosis in hippocampal slices but protect cortical cells in models of post-ischaemic brain damage. Br.J.Pharmacol. 157 854 PMID: 19422384
If you know of a relevant reference for UPF 1069, please let us know.
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Keywords: UPF 1069, supplier, PARP2, poly(ADP-ribose), polymerases, inhibitors, inhibits, UPF1069, Poly(ADP-ribose), Polymerase, Poly(ADP-ribose), Polymerase, Tocris Bioscience
Citations for UPF 1069
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