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Submit ReviewUMB 68
Discontinued Product
UMB 68 (Cat. No. 5518) has been withdrawn from sale for commercial reasons.
Description: GHB receptor ligand
Chemical Name: Sodium 4-Hydroxy-4methylpentanoate
Biological Activity for UMB 68
UMB 68 is a GHB receptor ligand. Exhibits similar receptor afffinity as GHB (IC50 for displacement of 3[H]NCS-382 from GHB receptors is 38 μM compared with 25 μM for GHB). Demonstrates no significant affinity for GABAB receptors and does not exhibit GHB-like behavioral effects in vivo.
Technical Data for UMB 68
| M. Wt | 154.14 |
| Formula | C6H11NaO3 |
| Storage | Desiccate at RT |
| CAS Number | 581099-89-0 |
| PubChem ID | 57340483 |
| InChI Key | RKKDHFJDHVHVLY-UHFFFAOYSA-M |
| Smiles | O=C(CCC(C)(O)C)O[Na] |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for UMB 68
References for UMB 68
References are publications that support the biological activity of the product.
Wu et al (2003) A tertiary alcohol analog of γ-hydroxybutyric acid as a specific γ-hydroxybutyric acid receptor ligand. J.Pharmacol.Exp.Ther. 305 675 PMID: 12606613
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Keywords: UMB 68, UMB 68 supplier, UMB68, gamma-hydroxybutyric, acid, γ, GHB, receptor, ligands, GABAb, GABAB, Receptors, 5518, Tocris Bioscience
Citations for UMB 68
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Currently there are no citations for UMB 68.
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