UMB 68

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Cat.No. 5518 - UMB 68 | C6H11NaO3 | CAS No. 581099-89-0
Description: GHB receptor ligand
Chemical Name: Sodium 4-Hydroxy-4methylpentanoate
Datasheet
Citations
Reviews
Literature

Biological Activity

GHB receptor ligand. Exhibits similar receptor afffinity as GHB (IC50 for displacement of 3[H]NCS-382 from GHB receptors is 38 μM compared with 25 μM for GHB). Demonstrates no significant affinity for GABAB receptors and does not exhibit GHB-like behavioral effects in vivo.

Technical Data

M. Wt 154.14
Formula C6H11NaO3
Storage Desiccate at RT
CAS Number 581099-89-0
PubChem ID 57340483
InChI Key RKKDHFJDHVHVLY-UHFFFAOYSA-M
Smiles O=C(CCC(C)(O)C)O[Na]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 15.41 100
water 15.41 100

Preparing Stock Solutions

The following data is based on the product molecular weight 154.14. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 6.49 mL 32.44 mL 64.88 mL
5 mM 1.3 mL 6.49 mL 12.98 mL
10 mM 0.65 mL 3.24 mL 6.49 mL
50 mM 0.13 mL 0.65 mL 1.3 mL

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Wu et al (2003) A tertiary alcohol analog of γ-hydroxybutyric acid as a specific γ-hydroxybutyric acid receptor ligand. J.Pharmacol.Exp.Ther. 305 675 PMID: 12606613


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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

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