UMB 68

Discontinued Product

UMB 68 (Cat. No. 5518) has been withdrawn from sale for commercial reasons.
Description: GHB receptor ligand
Chemical Name: Sodium 4-Hydroxy-4methylpentanoate
Literature (2)

Biological Activity for UMB 68

UMB 68 is a GHB receptor ligand. Exhibits similar receptor afffinity as GHB (IC50 for displacement of 3[H]NCS-382 from GHB receptors is 38 μM compared with 25 μM for GHB). Demonstrates no significant affinity for GABAB receptors and does not exhibit GHB-like behavioral effects in vivo.

Technical Data for UMB 68

M. Wt 154.14
Formula C6H11NaO3
Storage Desiccate at RT
CAS Number 581099-89-0
PubChem ID 57340483
Smiles O=C(CCC(C)(O)C)O[Na]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for UMB 68

References are publications that support the biological activity of the product.

Wu et al (2003) A tertiary alcohol analog of γ-hydroxybutyric acid as a specific γ-hydroxybutyric acid receptor ligand. J.Pharmacol.Exp.Ther. 305 675 PMID: 12606613

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Keywords: UMB 68, UMB 68 supplier, UMB68, gamma-hydroxybutyric, acid, γ, GHB, receptor, ligands, GABAb, GABAB, Receptors, 5518, Tocris Bioscience

Citations for UMB 68

Citations are publications that use Tocris products.

Currently there are no citations for UMB 68.

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

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GABA Receptors Scientific Review

GABA Receptors Scientific Review

Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.

Addiction Poster

Addiction Poster

The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.