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UBP 301 is a potent kainate receptor antagonist (apparent Kd = 5.94 μM). Displays ~ 30-fold selectivity over AMPA receptors.
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|DMSO||2.3||5 with gentle warming|
The following data is based on the product molecular weight 459.2. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.05 mM||43.55 mL||217.77 mL||435.54 mL|
|0.25 mM||8.71 mL||43.55 mL||87.11 mL|
|0.5 mM||4.36 mL||21.78 mL||43.55 mL|
|2.5 mM||0.87 mL||4.36 mL||8.71 mL|
References are publications that support the biological activity of the product.
More et al (2003) Structural requirements for novel willardiine derivatives acting as AMPA and kainate receptor antagonists. Br.J.Pharmacol. 138 1093 PMID: 12684265
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Keywords: UBP 301, UBP 301 supplier, Kainate, receptor, antagonists, Glutamate, Receptors, iGluR, Ionotropic, UBP301, 1766, Tocris Bioscience
Citations are publications that use Tocris products. Selected citations for UBP 301 include:
Cassé et al (2012) Glutamate controls tPA recycling by astrocytes, which in turn influences glutamatergic signals. J Neurosci 32 5186 PMID: 22496564
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
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