Trimethoprim

Discontinued Product

Unfortunately Trimethoprim (Cat. No. 0650) has been withdrawn from sale for commercial reasons.
Cat.No. 0650 - Trimethoprim | C14H18N4O3 | CAS No. 738-70-5
Description: Dihydrofolate reductase inhibitor
Purity: ≥98% (HPLC)
Datasheet
Citations
Literature

Biological Activity

Antibacterial. Potently inhibits bacterial and protozoal dihydrofolate reductase.

Technical Data

M. Wt 290.32
Formula C14H18N4O3
Storage Store at RT
Purity ≥98% (HPLC)
CAS Number 738-70-5
Smiles NC2=NC=C(C(N)=N2)CC1=CC(OC)=C(OC)C(OC)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 290.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.44 mL 17.22 mL 34.44 mL
5 mM 0.69 mL 3.44 mL 6.89 mL
10 mM 0.34 mL 1.72 mL 3.44 mL
50 mM 0.07 mL 0.34 mL 0.69 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

Product Datasheets

Certificate of Analysis is currently unavailable
on-line. Please contact Customer Service.
Safety Datasheet

References

References are publications that support the products' biological activity.

Brogden et al (1982) Trimethoprim: a review of its antibacterial activity, pharmacokinetics and therapeutic use in urinary tract infections. Drugs 23 405 PMID: 7049657

Merck Index 12 9840 PMID:

View Related Products by Target

View Related Products by Product Action

View all Dihydrofolate Reductase Inhibitors

Keywords: Trimethoprim, supplier, Dihydrofolate, reductase, inhibitors, inhibits, DHFR, Reductase, Reductases, antibacterial, Dihydrofolate, Reductase, Dihydrofolate, Reductase, Tocris Bioscience

Citations for Trimethoprim

Citations are publications that use Tocris products.

Currently there are no citations for Trimethoprim.

Commented out for usability testing

Reviews

TODO: Add Reviews

Literature in this Area

New Product Guide

New Product Guide (Spring/Summer 2017)

Our new product guide highlights over 130 new products added to the Tocris Bioscience range during the first half of 2017.

  • 7-TM Receptors
  • Enzymes
  • Enzyme-Linked Receptors
  • Ion Channels
  • Nuclear Receptors
  • Transporters
  • Apoptosis
  • Cell Metabolism
  • Epigenetics
  • Fluorescent Imaging
  • Signal Transduction
  • Stem Cells

Pathways for Trimethoprim

Protocols

TODO: Add Protocols