trans-Triprolidine hydrochloride

Discontinued Product

trans-Triprolidine hydrochloride (Cat. No. 0662) has been withdrawn from sale for commercial reasons.
Description: Highly potent H1 antagonist
Chemical Name: (E)-2-[1-(4-Methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]pyridine hydrochloride
Purity: ≥99% (HPLC)
Citations (2)
Literature (1)

Biological Activity for trans-Triprolidine hydrochloride

trans-Triprolidine hydrochloride is a potent H1 receptor antagonist.

Technical Data for trans-Triprolidine hydrochloride

M. Wt 314.86
Formula C19H22N2.HCl
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 550-70-9
PubChem ID 5702129
Smiles Cl[H].CC1=CC=C(C=C1)C(=C/CN1CCCC1)\C1=CC=CC=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for trans-Triprolidine hydrochloride

Certificate of Analysis / Product Datasheet
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References for trans-Triprolidine hydrochloride

References are publications that support the biological activity of the product.

Hill (1990) Distribution properties and functional characteristics of three classes of histamine receptor. Pharmacol.Rev. 42 45 PMID: 2164693

Merck Index 12 9877

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Keywords: trans-Triprolidine hydrochloride, trans-Triprolidine hydrochloride supplier, H1, antagonists, potent, Receptors, Histamine, histaminergic, 0662, Tocris Bioscience

2 Citations for trans-Triprolidine hydrochloride

Citations are publications that use Tocris products. Selected citations for trans-Triprolidine hydrochloride include:

Femenia et al (2015) Hippocampal-Dependent Antidepressant Action of the H3 Receptor Antagonist Clobenpropit in a Rat Model of Depression. Int J Neuropsychopharmacol 18 PMID: 25762718

Kwiatkowski et al (2013) Coordination of distinct but interacting rhythmic motor programs by a modulatory projection neuron using different co-transmitters in different ganglia. J Exp Biol 216 1827 PMID: 23393282

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Histamine Receptors Scientific Review

Histamine Receptors Scientific Review

Written by Iwan de Esch and Rob Leurs, this review provides a synopsis of the different histamine receptor subtypes and the ligands that act upon them; compounds available from Tocris are listed.