trans-Triprolidine hydrochloride

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Cat.No. 0662 - trans-Triprolidine hydrochloride | C19H22N2.HCl | CAS No. 550-70-9
Description: Standard H1 antagonist, highly potent
Chemical Name: (E)-2-[1-(4-Methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]pyridine hydrochloride
Purity: ≥99% (HPLC)
Datasheet
Citations (2)
Literature

Biological Activity

Potent H1 receptor antagonist.

Technical Data

M. Wt 314.86
Formula C19H22N2.HCl
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 550-70-9
PubChem ID 5702129
InChI Key WYUYEJNGHIOFOC-NWBUNABESA-N
Smiles Cl[H].CC1=CC=C(C=C1)C(=C/CN1CCCC1)\C1=CC=CC=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 31.49 100
water 31.49 100

Preparing Stock Solutions

The following data is based on the product molecular weight 314.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.18 mL 15.88 mL 31.76 mL
5 mM 0.64 mL 3.18 mL 6.35 mL
10 mM 0.32 mL 1.59 mL 3.18 mL
50 mM 0.06 mL 0.32 mL 0.64 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Hill (1990) Distribution properties and functional characteristics of three classes of histamine receptor. Pharmacol.Rev. 42 45 PMID: 2164693

Merck Index 12 9877 PMID:


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Keywords: trans-Triprolidine hydrochloride, supplier, H1, antagonists, potent, Receptors, Histamine, histaminergic, Histamine, H1, Receptors, Tocris Bioscience

2 Citations for trans-Triprolidine hydrochloride

Citations are publications that use Tocris products. Selected citations for trans-Triprolidine hydrochloride include:

Femenia et al (2015) Hippocampal-Dependent Antidepressant Action of the H3 Receptor Antagonist Clobenpropit in a Rat Model of Depression. Int J Neuropsychopharmacol 18 PMID: 25762718

Kwiatkowski et al (2013) Coordination of distinct but interacting rhythmic motor programs by a modulatory projection neuron using different co-transmitters in different ganglia. J Exp Biol 216 1827 PMID: 23393282


Do you know of a great paper that uses trans-Triprolidine hydrochloride from Tocris? If so please let us know.

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Histamine Receptors Scientific Review

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