trans-Triprolidine hydrochloride

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Cat.No. 0662 - trans-Triprolidine hydrochloride | C19H22N2.HCl | CAS No. 550-70-9
Description: Highly potent H1 antagonist
Chemical Name: (E)-2-[1-(4-Methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]pyridine hydrochloride
Purity: ≥99% (HPLC)
Datasheet
Citations (2)
Reviews
Literature

Biological Activity

Potent H1 receptor antagonist.

Technical Data

M. Wt 314.86
Formula C19H22N2.HCl
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 550-70-9
PubChem ID 5702129
InChI Key WYUYEJNGHIOFOC-NWBUNABESA-N
Smiles Cl[H].CC1=CC=C(C=C1)C(=C/CN1CCCC1)\C1=CC=CC=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 31.49 100

Preparing Stock Solutions

The following data is based on the product molecular weight 314.86. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.18 mL 15.88 mL 31.76 mL
5 mM 0.64 mL 3.18 mL 6.35 mL
10 mM 0.32 mL 1.59 mL 3.18 mL
50 mM 0.06 mL 0.32 mL 0.64 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Hill (1990) Distribution properties and functional characteristics of three classes of histamine receptor. Pharmacol.Rev. 42 45 PMID: 2164693

Merck Index 12 9877


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2 Citations for trans-Triprolidine hydrochloride

Citations are publications that use Tocris products. Selected citations for trans-Triprolidine hydrochloride include:

Femenia et al (2015) Hippocampal-Dependent Antidepressant Action of the H3 Receptor Antagonist Clobenpropit in a Rat Model of Depression. Int J Neuropsychopharmacol 18 PMID: 25762718

Kwiatkowski et al (2013) Coordination of distinct but interacting rhythmic motor programs by a modulatory projection neuron using different co-transmitters in different ganglia. J Exp Biol 216 1827 PMID: 23393282


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