Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit Reviewtrans-Triprolidine hydrochloride
Description: Highly potent H1 antagonist
Chemical Name: (E)-2-[1-(4-Methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]pyridine hydrochloride
Purity: ≥99% (HPLC)
Biological Activity
Potent H1 receptor antagonist.
Technical Data
| M. Wt | 314.86 |
| Formula | C19H22N2.HCl |
| Storage | Store at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 550-70-9 |
| PubChem ID | 5702129 |
| InChI Key | WYUYEJNGHIOFOC-NWBUNABESA-N |
| Smiles | Cl[H].CC1=CC=C(C=C1)C(=C/CN1CCCC1)\C1=CC=CC=N1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 31.49 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 314.86. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.18 mL | 15.88 mL | 31.76 mL |
| 5 mM | 0.64 mL | 3.18 mL | 6.35 mL |
| 10 mM | 0.32 mL | 1.59 mL | 3.18 mL |
| 50 mM | 0.06 mL | 0.32 mL | 0.64 mL |
Molarity Calculator
Molarity Calculator
Calculate the mass, volume, or concentration required for a solution.
Reconstitution Calculator
Reconstitution Calculator
Dilution Calculator
Dilution Calculator
Calculate the dilution required to prepare a stock solution.
Product Datasheets
References
References are publications that support the biological activity of the product.
Hill (1990) Distribution properties and functional characteristics of three classes of histamine receptor. Pharmacol.Rev. 42 45 PMID: 2164693
Merck Index 12 9877
If you know of a relevant reference for trans-Triprolidine hydrochloride, please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: trans-Triprolidine hydrochloride, trans-Triprolidine hydrochloride supplier, H1, antagonists, potent, Receptors, Histamine, histaminergic, 0662, Tocris Bioscience
2 Citations for trans-Triprolidine hydrochloride
Citations are publications that use Tocris products. Selected citations for trans-Triprolidine hydrochloride include:
Femenia et al (2015) Hippocampal-Dependent Antidepressant Action of the H3 Receptor Antagonist Clobenpropit in a Rat Model of Depression. Int J Neuropsychopharmacol 18 PMID: 25762718
Kwiatkowski et al (2013) Coordination of distinct but interacting rhythmic motor programs by a modulatory projection neuron using different co-transmitters in different ganglia. J Exp Biol 216 1827 PMID: 23393282
Do you know of a great paper that uses trans-Triprolidine hydrochloride from Tocris? Please let us know.
Reviews for trans-Triprolidine hydrochloride
There are currently no reviews for this product. Be the first to review trans-Triprolidine hydrochloride and earn rewards!
Have you used trans-Triprolidine hydrochloride?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
GPCR Product Listing
A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:
- Rhodopsin-like Receptors
- Glutamate Receptors
- Frizzled Receptors
- GPCR Signaling
Histamine Receptors Scientific Review
Written by Iwan de Esch and Rob Leurs, this review provides a synopsis of the different histamine receptor subtypes and the ligands that act upon them; compounds available from Tocris are listed.
Asthma Poster
Asthma is one of the most common chronic diseases in the world, affecting over 300 million people. This poster highlights key pathways and new therapies used to treat the condition, including those currently in clinical development.