Histamine Receptors Scientific Review

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Histamine Receptors Scientific Review

Iwan de Esch and Rob Leurs, Vrije University

Review excerpt: "Histamine is one of the main aminergic neurotransmitters and plays an important role in the regulation of several (patho)physiological processes. In the mammalian brain histamine is synthesized in restricted populations of neurons. These neurons project diffusely to most cerebral areas and have been implicated in several brain functions (e.g. sleep/wakefulness, hormonal secretion, cardiovascular control, thermoregulation, food intake, and memory formation)."