Tocriscreen Kinase Inhibitor Library

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Cat.No. 6268 - Tocriscreen Kinase Inhibitor Library
Description: A bioactive compound library of 160 kinase inhibitors (250 μL 10 mM DMSO solutions) for high-throughput screening, high-content screening and chemical biology applications
Datasheet
Citations (11)
Reviews
Literature (1)

Biological Activity

A collection of 160 kinase inhibitors supplied pre-dissolved in DMSO (250 μL 10 mM solution). The Tocriscreen Kinase Inhibitor Library contains compounds targeting >60 different kinases, including extensive coverage of well-established targets such as VEFGR, AKT and TGFβR as well as more novel targets such as LIMK, Hapsin, NUAK1 and DYRK.

If this library does not suit your needs, please submit your requirements through our Tocriscreen PRO custom compound library service.

Key Format and Product Details

  • 96-well racks with Matrix storage tubes & SepraSeal caps
  • Pre-dissolved in DMSO
  • Compounds arranged 80 per rack with two racks per library
  • Many compounds are exclusive to Tocris
  • Full chemical and biological data available
  • Exceptional purity
Target Classes Covered by the Tocriscreen Kinases Inhibitors Library

The Tocriscreen Kinase Inhibitors Library contains bioactive compounds covering a diverse range of kinases, including established enzymes and more novel targets.

Request Compound List

To request a list of the compounds available in the Tocriscreen Kinase Inhibitor Library please click the request tile below. Compound lists can be provided in Excel or SD format.

Request compound list for Tocriscreen Kinase Inhibitor Library

Technical Data

Storage Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service

References

References are publications that support the biological activity of the product.

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View Related Products by Target

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11 Citations for Tocriscreen Kinase Inhibitor Library

Citations are publications that use Tocris products. Selected citations for Tocriscreen Kinase Inhibitor Library include:

FitzGerald et al (2014) A high through-put screen for small molecules modulating MCM2 phosphorylation identifies Ryuvidine as an inducer of the DNA damage response. PLoS One 9 e98891 PMID: 24902048

Acevedo et al (2014) Phosphorylation of amyloid precursor protein at threonine 668 is essential for its copper-responsive trafficking in SH-SY5Y neuroblastoma cells. J Biol Chem 289 11007 PMID: 24610780

Chaudhari et al (2019) Transient c-Src Suppression During Endodermal Commitment of Human Induced Pluripotent Stem Cells Results in Abnormal Profibrotic Cholangiocyte-Like Cells. Stem Cells 37 306 PMID: 30471152

Yang et al (2019) NTRK1 is a positive regulator of YAP oncogenic function. Oncogene 38 2778 PMID: 30542115


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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Tocriscreen Compound Libraries

Tocriscreen Compound Libraries

This brochure gives an overview of the unique TocriscreenTM bioactive compound library range, including

  • Tocriscreen 2.0 Compound Library
  • Focussed Tocriscreen Libraries
  • Tocriscreen FDA-approved Drug Library
  • Tocriscreen PRO Custom Service