Tocriscreen Kinase Inhibitor Library

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Cat.No. 6268 - Tocriscreen Kinase Inhibitor Library
Description: A library of 160 kinase inhibitor compounds (250 μL 10 mM DMSO solutions)
Datasheet
Citations (7)
Reviews

Biological Activity

A collection of 160 kinase inhibitors supplied pre-dissolved in DMSO (250 μL 10 mM solution). The Tocriscreen Kinase Inhibitor Library contains compounds targeting >60 different kinases, including extensive coverage of well-established targets such as VEFGR, AKT and TGFβR as well as more novel targets such as LIMK, Hapsin, NUAK1 and DYRK.

Key Format and Product Details

  • 96-well racks with Matrix storage tubes & SepraSeal caps
  • Pre-dissolved in DMSO
  • Compounds arranged 80 per rack with two racks per library
  • Many compounds are exclusive to Tocris
  • Full chemical and biological data available
  • Exceptional purity

Request Compound List

To request a list of the compounds available in the Tocriscreen Kinase Inhibitor Library please click the request tile below. Compound lists can be provided in Excel or SD format.

Request compound list for Tocriscreen Kinase Inhibitor Library

Technical Data

Storage Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Certificate of Analysis is currently unavailable on-line.
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References

References are publications that support the biological activity of the product.

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7 Citations for Tocriscreen Kinase Inhibitor Library

Citations are publications that use Tocris products. Selected citations for Tocriscreen Kinase Inhibitor Library include:

Markussen et al (2018) GSK3 is a negative regulator of the thermogenic program in brown adipocytes. Sci.Rep. 8 3469 PMID: 29472592

Sherman and Rossi (2019) A Novel Three-Dimensional Glioma Blood-Brain Barrier Model for High-Throughput Testing of Tumoricidal Capability. Front Oncol 9 351 PMID: 31131260

Moeschler et al (2018) 1-Benzyl-3-cetyl-2-methylimidazolium Iodide (NH125) Is a Broad-Spectrum Inhibitor of Virus Entry with Lysosomotropic Features. Viruses 10 E306 PMID: 29874821

Moujalled et al (2013) Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress. PLoS One 8 e67433 PMID: 23840699


Do you know of a great paper that uses Tocriscreen Kinase Inhibitor Library from Tocris? Please let us know.

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