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Tocriscreen Kinase Inhibitor Toolbox
A collection of 80 kinase inhibitors supplied as pre-dissolved DMSO solutions (250 μl 10 mM solution per compound).
Key Format and Product Details
- 96-well rack with Matrix storage tubes & SepraSeal caps
- Pre-dissolved in DMSO
- All compounds are biologically active
- Full chemical and biological data available
- Exceptional purity
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Jester et al (2010) A coiled-coil enabled split-luciferase three-hybrid system: applied toward profiling inhibitors of protein kinases. J.Am.Chem.Soc. 132 11727 PMID: 20669947
Moujalled et al (2013) Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress. PLoS ONE 8 e67433 PMID: 23840699
Keywords: Tocriscreen Kinase Inhibitor Toolbox, Tocriscreen Kinase Inhibitor Toolbox supplier, , Tocris Bioscience
6 Citations for Tocriscreen Kinase Inhibitor Toolbox
Citations are publications that use Tocris products. Selected citations for Tocriscreen Kinase Inhibitor Toolbox include:
Yang et al (2019) NTRK1 is a positive regulator of YAP oncogenic function. Oncogene 38 2778 PMID: 30542115
Chaudhari et al (2019) Transient c-Src Suppression During Endodermal Commitment of Human Induced Pluripotent Stem Cells Results in Abnormal Profibrotic Cholangiocyte-Like Cells. Stem Cells 37 306 PMID: 30471152
Azad et al (2018) A LATS biosensor screen identifies VEGFR as a regulator of the Hippo pathway in angiogenesis. Nat Commun 9 1061 PMID: 29535383
Moujalled et al (2013) Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress. PLoS One 8 e67433 PMID: 23840699
Acevedo et al (2014) Phosphorylation of amyloid precursor protein at threonine 668 is essential for its copper-responsive trafficking in SH-SY5Y neuroblastoma cells. Cancer Sci 289 11007 PMID: 24610780
FitzGerald et al (2014) A high through-put screen for small molecules modulating MCM2 phosphorylation identifies Ryuvidine as an inducer of the DNA damage response. PLoS One 9 e98891 PMID: 24902048
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