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Selective P2Y12 receptor antagonist. Inhibits ADP-induced platelet aggregation and displays antithrombotic activity following oral administration in vivo.
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 300.25. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.33 mL||16.65 mL||33.31 mL|
|5 mM||0.67 mL||3.33 mL||6.66 mL|
|10 mM||0.33 mL||1.67 mL||3.33 mL|
|50 mM||0.07 mL||0.33 mL||0.67 mL|
References are publications that support the biological activity of the product.
Michelson (2008) P2Y12 antagonism: promises and challenges. Arterioscler.Thromb.Vasc.Biol. 28 33
Savi and Herbert (2005) Clopidogrel and ticlopidine: P2Y12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis. Semin.Thromb.Haemostas. 31 174
Sharis et al (1998) The antiplatelet effects of ticlop. and clopid. Ann.Int.Med. 129 394
If you know of a relevant reference for Ticlopidine hydrochloride, please let us know.
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Keywords: Ticlopidine hydrochloride, Ticlopidine hydrochloride supplier, selective, P2Y12, purinergic, receptors, purinoceptors, antagonists, Purinergic, P2Y, Receptors, 3931, Tocris Bioscience
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Literature in this Area
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