TFMPP hydrochloride

Discontinued Product

TFMPP hydrochloride (Cat. No. 0968) has been withdrawn from sale for commercial reasons.
Cat.No. 0968 - TFMPP hydrochloride | CAS No. 16015-69-3
Description: 5-HT1B partial agonist
Chemical Name: N-(3-Trifluoromethylphenyl)piperazine hydrochloride
Purity: ≥99% (HPLC)
Datasheet
Citations
Reviews
Literature

Biological Activity

Partial agonist with some preference for 5-HT1B receptors; displays similar potency at 5-HT1A and 5-HT2C receptors.

Technical Data

M. Wt 266.69
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 16015-69-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Product Datasheets

Certificate of Analysis is currently unavailable on-line.
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Safety Datasheet

References

References are publications that support the biological activity of the product.

Chaouloff et al (1998) GR 127935 and (+)-WAY 100135 do not affect TFMPP-induced inhibition of 5-HT synthesis in the midbrain and hippocampus of Wistar-Kyoto rats. Neuropharmacology 37 1159 PMID: 9833646

Lucki et al (1989) Effect of 1-(m-chlorophenyl)piperazine and 1-(m-trifluoromethylphenyl)piperazine on locomotor activity. J.Pharmacol.Exp.Ther. 249 155 PMID: 2709329

Schoeffter and Hoyer (1989) Interaction of arylpiperazines with 5-HT1A, 5-HT1B, 5-HT1C and 5-HT1D receptors: do discriminatory 5-HT1B receptor ligands exist? Naunyn Schmiedebergs Arch.Pharmacol. 339 675 PMID: 2770889

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Citations for TFMPP hydrochloride

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