Selective inhibitor of Bruton's tyrosine kinase (BTK). Inhibits the interaction between PKCbII and BTK (IC50 ~ 30 mM) and the catalytic activity of BTK but does not affect the activity of PKC. Has little effect on the activities of Lyn, Syk, PKA, casein kinase I, ERK1, ERK2 and p38 kinases.
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 154.12. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.2 mM||32.44 mL||162.21 mL||324.42 mL|
|1 mM||6.49 mL||32.44 mL||64.88 mL|
|2 mM||3.24 mL||16.22 mL||32.44 mL|
|10 mM||0.65 mL||3.24 mL||6.49 mL|
References are publications that support the biological activity of the product.
Kawakami et al (1999) Terreic acid, a quinone epoxide inhibitor of Bruton's tyrosine kinase. Proc.Natl.Acad.Sci.U.S.A. 96 2227 PMID: 10051623
Subramanian et al (1982) In vivo and in vitro studies on the binding nature of terreic acid with macromolecules such as protein and nucleic acids. Toxicol.Lett. 10 249 PMID: 7080093
Yamamoto et al (1980) Studies on terreic acid. Jpn.J.Antibiot. 33 320 PMID: 7190624
If you know of a relevant reference for (-)-Terreic acid, please let us know.
View Related Products by Product Action
Keywords: Terreic acid, Terreic acid supplier, Selective, inhibitors, inhibits, BTK, Brutons, Tyrosine, Kinases, Kinase, (BTK), 1405, Tocris Bioscience
Citations for (-)-Terreic acid
Citations are publications that use Tocris products.
Currently there are no citations for (-)-Terreic acid. Do you know of a great paper that uses (-)-Terreic acid from Tocris? Please let us know.
Reviews for (-)-Terreic acid
There are currently no reviews for this product. Be the first to review (-)-Terreic acid and earn rewards!
Have you used (-)-Terreic acid?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.