Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewTDFA
Discontinued Product
5482 has been discontinued.
View all Post-translational Modifications products.
Description: PAD4 inhibitor
Biological Activity for TDFA
Protein arginine deiminase 4 (PAD4) inhibitor (IC50 values are 2.3, 8.5, 26 and 71 μM for PAD4, PAD1, PAD3 and PAD2, respectively).
Technical Data for TDFA
| M. Wt | 448.45 |
| Formula | C17H29FN6O7 |
| Sequence |
Ac-TD-X (Modifications: Thr-1 = N-terminal Ac, X = N5-(2-fluoro-1-iminoethyl)]-Orn), X-3= C-terminal amide) |
| Storage | Store at -20°C |
| CAS Number | 1345019-64-8 |
| PubChem ID | 121513865 |
| InChI Key | SOZMHIJABUOUSN-ORMVGFHCSA-N |
| Smiles | [H]N([C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(=N)CF)C(N)=O)C(C)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for TDFA
References for TDFA
References are publications that support the biological activity of the product.
Jones et al (2012) Synthesis and screening of a haloacetamidine containing library to identify PAD4 selective inhibitors. ACS Chem.Biol. 7 160 PMID: 22004374
View Related Products by Target
View Related Products by Product Action
Keywords: TDFA, TDFA supplier, PAD4, protein, arginine, deiminase, 4, inhibits, inhibitors, Post-translational, Modifications, 5482, Tocris Bioscience
Citations for TDFA
Citations are publications that use Tocris products.
Currently there are no citations for TDFA.
Reviews for TDFA
There are currently no reviews for this product. Be the first to review TDFA and earn rewards!
Have you used TDFA?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image