Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
T 26c disodium salt is a highly potent and selective MMP13 inhibitor (IC50 = 6.9 pM). Exhibits >2600-fold selectivity for MMP13 over related MMPs. Inhibits degradation of bovine nasal septum cartilage explants in vitro . Orally bioavailable.
This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the T-26c probe summary on the SGC website.
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|DMSO||5.23||10 with gentle warming|
The following data is based on the product molecular weight 523.47. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||19.1 mL||95.52 mL||191.03 mL|
|0.5 mM||3.82 mL||19.1 mL||38.21 mL|
|1 mM||1.91 mL||9.55 mL||19.1 mL|
|5 mM||0.38 mL||1.91 mL||3.82 mL|
References are publications that support the biological activity of the product.
Nara et al (2014) Thieno[2,3-d]pyrimidine-2-carboxamides bearing a carboxybenzene group at 5-position: highly potent, selective, and orally available MMP-13 inhibitors interacting with the S1" binding site. Bioorg.Med.Chem. 22 5487 PMID: 25192810
If you know of a relevant reference for T 26c disodium salt, please let us know.
Keywords: T 26c disodium salt, T 26c disodium salt supplier, T26c, disodium, salt, matrix, metalloproteases, inhibitors, inhibits, MMP13, selective, highly, potent, orally, bioavailable, Matrix, Metalloprotease, 6134, Tocris Bioscience
Citations are publications that use Tocris products.
Currently there are no citations for T 26c disodium salt. Do you know of a great paper that uses T 26c disodium salt from Tocris? Please let us know.
There are currently no reviews for this product. Be the first to review T 26c disodium salt and earn rewards!
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.