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Discontinued ProductStrychnine hydrochloride (Cat. No. 2785) has been withdrawn from sale for commercial reasons.
Competitive glycine receptor antagonist; convulsant. Also nicotinic receptor antagonist; displays competitive antagonism at α7 receptors and non-competitive antagonism at α4β2 receptors.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Mataubayashi et al (1998) Strychnine: a potent competitive antagonist of α-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat hippocampal neurons. J.Pharmacol.Exp.Ther. 284 904 PMID: 9495848
Betz et al (2006) Glycine receptors: recent insights into their structural organization and functional diversity. J.Neurochem. 67 1600
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Keywords: Strychnine hydrochloride, Strychnine hydrochloride supplier, Competitive, glycine, receptors, antagonists, Nicotinic, GlyR, Acetylcholine, Non-Selective, Subtypes, nAChR, a7, α7, alpha7, α4β2, a4b2, Glycine, Receptors, (Non-selective), 2785, Tocris Bioscience
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