Discontinued ProductUnfortunately Strychnine hydrochloride (Cat. No. 2785) has been withdrawn from sale for commercial reasons.
Competitive glycine receptor antagonist; convulsant. Also nicotinic receptor antagonist; displays competitive antagonism at α7 receptors and non-competitive antagonism at α4β2 receptors.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Preparing Stock Solutions
The following data is based on the product molecular weight 370.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.7 mL||13.48 mL||26.96 mL|
|5 mM||0.54 mL||2.7 mL||5.39 mL|
|10 mM||0.27 mL||1.35 mL||2.7 mL|
|50 mM||0.05 mL||0.27 mL||0.54 mL|
References are publications that support the products' biological activity.
Mataubayashi et al (1998) Strychnine: a potent competitive antagonist of α-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat hippocampal neurons. J.Pharmacol.Exp.Ther. 284 904 PMID: 9495848
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Keywords: Strychnine hydrochloride, supplier, Competitive, glycine, receptors, antagonists, Nicotinic, GlyR, Acetylcholine, Non-Selective, Subtypes, nAChR, a7, α7, alpha7, α4β2, a4b2, Glycine, Receptors, Nicotinic, Receptors, (Non-selective), Glycine, Receptors, Tocris Bioscience
Citations for Strychnine hydrochloride
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Currently there are no citations for Strychnine hydrochloride.
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