Small molecule that primes embryonic stem cells (ESCs) for differentiation. Interacts with NME2 and inhibits its nuclear translocation. Increases the efficiency of directed differentiation of mouse and human ESCs in vitro.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble in DMSO|
Preparing Stock Solutions
The following data is based on the product molecular weight 584.62. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.71 mL||8.55 mL||17.11 mL|
|5 mM||0.34 mL||1.71 mL||3.42 mL|
|10 mM||0.17 mL||0.86 mL||1.71 mL|
|50 mM||0.03 mL||0.17 mL||0.34 mL|
References are publications that support the biological activity of the product.
Zhu et al (2009) A small molecule primes embryonic stem cells for differentiation. Cell Stem Cell. 4 416 PMID: 19427291
If you know of a relevant reference for Stauprimide, please let us know.
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Keywords: Stauprimide, Stauprimide supplier, embryonic, stem, cells, ESCs, differentiation, inhibitors, inhibits, NME2, nuclear, translocation, transcription, factors, primes, Other, Transcription, Factors, and, iPSC, 3741, Tocris Bioscience
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Literature in this Area
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New Product Guide (Spring/Summer 2018)New
Our new product guide highlights over 200 new products added to the Tocris Bioscience range during the second half of 2017.
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- Stem Cells