st-Ht31

Pricing Availability   Qty
Cat.No. 6286 - st-Ht31 | Ste-Asp-Leu-Ile-Glu-Glu-Ala-Ala-Ser-Arg-Ile-Val-Asp-Ala-Val-Ile-Glu-Gln-Val-Lys-Ala-Ala-Gly-Ala-Tyr | CAS No. 188425-80-1
Description: Inhibits PKA/AKAP interactions; cell permeable
Datasheet
Citations
Reviews
Literature

Biological Activity

Stearated form of the peptide Ht-31. Inhibits the interaction between the RII subunits of cAMP-dependent PKA and A-kinase anchoring protein (AKAP) in cell extracts. Cell permeable.

Technical Data

M. Wt 2798.27
Formula C129H217N29O39
Sequence DLIEEAASRIVDAVIEQVKAAGAY

(Modifications: Asp-1 = N-terminal Ste)

Storage Store at -20°C
CAS Number 188425-80-1
PubChem ID 16143012
InChI Key AHVAWKAVLPRRQS-MUBBMYIHSA-N
Smiles CCCCCCCCCCCCCCCCCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solubility Soluble to 1 mg/ml in 0.1% Ammonia

Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Gorshkov et al (2017) AKAP-mediated feedback control of cAMP gradients in developing hippocampal neurons. Nat.Chem.Biol. 13 425 PMID: 28192412

Vijayaraghavan et al (1997) Protein kinase A-anchoring inhibitor peptides arrest mammalian sperm motility. J.Biol.Chem. 272 4747 PMID: 9030527

Carr et al (1992) Association of the type II cAMP-dependent protein kinase with a human thyroid RII-anchoring protein. Cloning and characterization of the RII-binding domain. J.Biol.Chem. 267 13376 PMID: 1618839


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Keywords: st-Ht31, st-Ht31 supplier, st_Ht31, st, Ht, 31, stearated, A-kinase, anchoring, protein, AKAP, cAMP-dependent, PKA, scaffolding, proteins, Protein, Kinase, A, A-kinase-anchoring, protiens, 6286, Tocris Bioscience

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