st-Ht31

Pricing Availability Delivery Time Qty
Cat.No. 6286 - st-Ht31 | Ste-Asp-Leu-Ile-Glu-Glu-Ala-Ala-Ser-Arg-Ile-Val-Asp-Ala-Val-Ile-Glu-Gln-Val-Lys-Ala-Ala-Gly-Ala-Tyr | CAS No. 188425-80-1
Description: Inhibits PKA/AKAP interactions; cell permeable
Datasheet
Citations
Literature

Biological Activity

Stearated form of the peptide Ht-31. Inhibits the interaction between the RII subunits of cAMP-dependent PKA and A-kinase anchoring protein (AKAP) in cell extracts. Cell permeable.

Technical Data

M. Wt 2798.27
Formula C129H217N29O39
Sequence DLIEEAASRIVDAVIEQVKAAGAY

(Modifications: Asp-1 = N-terminal Ste)

Storage Store at -20°C
CAS Number 188425-80-1
PubChem ID 16143012
InChI Key AHVAWKAVLPRRQS-MUBBMYIHSA-N
Smiles CCCCCCCCCCCCCCCCCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 1 mg/ml in 0.1% Ammonia

Preparing Stock Solutions

The following data is based on the product molecular weight 2798.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.36 mL 1.79 mL 3.57 mL
5 mM 0.07 mL 0.36 mL 0.71 mL
10 mM 0.04 mL 0.18 mL 0.36 mL
50 mM 0.01 mL 0.04 mL 0.07 mL

Molarity Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Gorshkov et al (2017) AKAP-mediated feedback control of cAMP gradients in developing hippocampal neurons. Nat.Chem.Biol. 13 425 PMID: 28192412

Vijayaraghavan et al (1997) Protein kinase A-anchoring inhibitor peptides arrest mammalian sperm motility. J.Biol.Chem. 272 4747 PMID: 9030527

Carr et al (1992) Association of the type II cAMP-dependent protein kinase with a human thyroid RII-anchoring protein. Cloning and characterization of the RII-binding domain. J.Biol.Chem. 267 13376 PMID: 1618839


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Keywords: st-Ht31, supplier, st_Ht31, st, Ht, 31, stearated, A-kinase, anchoring, protein, AKAP, cAMP-dependent, PKA, scaffolding, proteins, Protein, Kinase, A, A-kinase-anchoring, protiens, Protein, Kinase, A, Tocris Bioscience

Citations for st-Ht31

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