ST 91

Discontinued Product

ST 91 (Cat. No. 2638) has been withdrawn from sale for commercial reasons.
Description: α2 agonist, putative α2C agonist
Chemical Name: N-(2,6-Diethylphenyl)-4,5-dihydro-1H-imidazol-2-amine hydrochloride
Purity: ≥99% (HPLC)
Citations (1)
Literature (2)

Biological Activity for ST 91

ST 91 is an α2-adrenoceptor agonist that does not cross the blood brain barrier. Displays ~ 120-fold selectivity for α2 receptors over α1 receptors and acts predominantly at non-α2A-adrenoceptors which may be of the α2C subtype. Antinociceptive; increases tail-flick latencies in Sasco and Harlan rats.

Technical Data for ST 91

M. Wt 253.77
Formula C13H19N3.HCl
Storage Desiccate at +4°C
Purity ≥99% (HPLC)
CAS Number 4749-61-5
PubChem ID 20863
Smiles CCC2=C(C(CC)=CC=C2)/N=C1NCCN/1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for ST 91

References are publications that support the biological activity of the product.

Takano and Yaksh (1992) Characterization of the pharmacology of intrathecally administered alpha-2 agonists and antagonists in rats. J.Pharmacol.Exp.Ther. 261 764 PMID: 1349648

Celly et al (1999) Cardiopulmonary effects of the α2-adrenoceptor agonists medetomidine and ST-91 in anesthetized sheep. J.Pharmacol.Exp.Ther. 289 712 PMID: 10215644

Graham et al (2000) Synergistic interactions between two α2-adrenoceptor agonists, dexmedetom. and ST-91, in two substrains of Sprague-Dawley rats. Pain 85 135 PMID: 10692612

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Keywords: ST 91, ST 91 supplier, α2-adrenoceptor, alpha2-adrenoceptors, a2-adrenoceptors, α2-Adrenergic, alpha2-Adrenergic, a2-adrenergic, agonists, putative, α2C-adrenoceptor, alpha2C-adrenoceptors, α2c-adrenergic, alpha2c-adrenergic, a2c-adrenoceptor, a2c-adrenergic, Receptors, ST, Adrenergic, Alpha-2, 2638, Tocris Bioscience

1 Citation for ST 91

Citations are publications that use Tocris products. Selected citations for ST 91 include:

Kim et al (2011) Icilin-evoked behavioral stimulation is attenuated by alpha2-adrenoceptor activation. Brain Res 1384 110 PMID: 21315691

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

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