SDZ 205-557 hydrochloride
5-HT3/5-HT4 receptor antagonist.
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 337.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.97 mL||14.83 mL||29.65 mL|
|5 mM||0.59 mL||2.97 mL||5.93 mL|
|10 mM||0.3 mL||1.48 mL||2.97 mL|
|50 mM||0.06 mL||0.3 mL||0.59 mL|
References are publications that support the products' biological activity.
Eglen et al (1993) The action of SDZ 205,557 at 5-hydroxytryptamine (5-HT3 and 5-HT4) receptors. Br.J.Pharmacol. 108 376 PMID: 8448587
McMahon and Cunningham (1999) Antagonism of 5-hydroxytryptamine(4) receptors attenuates hyperactivity induced by cocaine: putative role for 5-hydroxytryptamine(4) receptors in the nucleus accumbens shell. J.Pharmacol.Exp.Ther. 291 300 PMID: 10490917
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Literature in this Area
5-HT Receptors Scientific Review
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