SC-9

Pricing Availability   Qty
Cat.No. 0433 - SC-9 | C22H24ClNO2S | CAS No. 102649-78-5
Description: Protein kinase C activator
Chemical Name: 5-Chloro-N-(6-phenylhexyl)-1-naphthalenesulfonamide
Purity: ≥99% (HPLC)
Datasheet
Citations
Reviews (1)
Literature

Biological Activity

A potent activator of protein kinase C.

Compound Libraries

SC-9 is also offered as part of the Tocriscreen Plus. Find out more about compound libraries available from Tocris.

Technical Data

M. Wt 401.95
Formula C22H24ClNO2S
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 102649-78-5
PubChem ID 124172
InChI Key YUXMTDYHFPRPLG-UHFFFAOYSA-N
Smiles ClC1=C2C=CC=C(C2=CC=C1)S(=O)(=O)NCCCCCCC1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
ethanol 10.05 25
DMSO 40.2 100

Preparing Stock Solutions

The following data is based on the product molecular weight 401.95. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.49 mL 12.44 mL 24.88 mL
5 mM 0.5 mL 2.49 mL 4.98 mL
10 mM 0.25 mL 1.24 mL 2.49 mL
50 mM 0.05 mL 0.25 mL 0.5 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

Product Datasheets

Certificate of Analysis / Product Datasheet
Select another batch:

References

References are publications that support the biological activity of the product.

Ito et al (1986) N-(6-Phenylhexyl)-5-chloro-1-naphthalenesulfonamide, a novel activator of protein kinase C. Biochemistry 25 4179 PMID: 3756133

Nishino et al (1986) N-(6-Phenylhexyl)-5-chloro-1-naphthalenesulfonamide is one of a new class of activators for Ca2+ -activated, phospholipid-dependent protein kinase. Biochim.Biophys.Acta. 889 236 PMID: 3778949


If you know of a relevant reference for SC-9, please let us know.

View Related Products by Product Action

View all Protein Kinase C Activators

Keywords: SC-9, SC-9 supplier, Protein, kinase, C, activators, PKC, PKM, Kinases, Kinase, Enzyme, Substrates, /, Activators, 0433, Tocris Bioscience

Citations for SC-9

Citations are publications that use Tocris products.

Currently there are no citations for SC-9. Do you know of a great paper that uses SC-9 from Tocris? Please let us know.

Reviews for SC-9

Average Rating: 5 (Based on 1 Review.)

5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%

Have you used SC-9?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Filter by:


Clot lysis activity screening of crude enzymes assessed.
By Anonymous on 11/13/2018
Assay Type: In Vitro
Species: Human

The clot lysis activity screening of the crude enzymes (100µl each) was done as triplet on 0.5 ml human blood with SC-9 kinase (30,000 IU/ml) as positive control and distilled water as negative thrombolytic control. All the crude enzymes of mutated Isolates showed good clot lysis activity.

review image

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Cancer

Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

  • Cancer Metabolism
  • Epigenetics in Cancer
  • Receptor Signaling
  • Cell Cycle and DNA Damage Repair
  • Angiogenesis
  • Invasion and Metastasis
Kinases

Kinases Product Listing

A collection of over 400 products for kinase research, the listing includes inhibitors of:

  • Receptor Tyrosine Kinases
  • Protein Kinases A, C, D and G
  • PI-3 Kinase, Akt and mTOR
  • MAPK Signaling
  • Receptor Serine/Threonine Kinases
Pain

Pain Research Product Guide

A collection of over 250 products for pain research, the guide includes research tools for the study of:

  • Nociception
  • Ion Channels
  • G-Protein-Coupled Receptors
  • Intracellular Signaling