Substrate for AMP-activated protein kinase (AMPK). Phosphorylated rapidly by AMPK, it is more specific for the kinase than acetyl CoA carboxylase itself, and provides a convenient and sensitive assay for AMPK.
|Storage||Desiccate at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solubility||Soluble to 1 mg/ml in water|
Preparing Stock Solutions
The following data is based on the product molecular weight 1779.15. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||0.56 mL||2.81 mL||5.62 mL|
|5 mM||0.11 mL||0.56 mL||1.12 mL|
|10 mM||0.06 mL||0.28 mL||0.56 mL|
|50 mM||0.01 mL||0.06 mL||0.11 mL|
References are publications that support the biological activity of the product.
Carling et al (1989) Purification and characterization of the AMP-activated protein kinase. Eur.J.Biochem. 186 129 PMID: 2598924
Davies et al (1989) Tissue distribution of the AMP-activated protein kinase, and lack of activation by cyclic-AMP-dependent protein kinase, studied using a specific and sensitive peptide assay. Eur.J.Biochem. 186 123 PMID: 2574667
Hardie et al (1998) The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell? Annu.Rev.Biochem 67 821 PMID: 9759505
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Keywords: SAMS Peptide, SAMS Peptide supplier, AMP-activated, protein, kinase, AMPK, Kinases, Enzyme, Substrates, Activators, /, 1344, Tocris Bioscience
1 Citation for SAMS Peptide
Citations are publications that use Tocris products. Selected citations for SAMS Peptide include:
Thelander et al (2004) Snf1-related protein kinase 1 is needed for growth in a normal day-night light cycle. EMBO J 23 1900 PMID: 15057278
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Literature in this Area
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