Salinomycin sodium salt
Cytotoxic to breast cancer stem cells. Inhibits CD44 expression in breast cancer cells in vitro. Inhibits mammary tumor growth in mice. Also antibiotic.
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 772.98. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.29 mL||6.47 mL||12.94 mL|
|5 mM||0.26 mL||1.29 mL||2.59 mL|
|10 mM||0.13 mL||0.65 mL||1.29 mL|
|50 mM||0.03 mL||0.13 mL||0.26 mL|
References are publications that support the biological activity of the product.
Gupta et al (2009) Identification of selective inhibitors of cancer stem cells by high-throughput screening. Cell 138 645 PMID: 19682730
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