Salinomycin sodium salt

Discontinued Product

Salinomycin sodium salt (Cat. No. 3637) has been withdrawn from sale for commercial reasons.
Description: Antibiotic; also selectively inhibits cancer stem cells
Chemical Name: (2R)-2-[(2R,5S,6R)-6-[(3S,5S,7R,9S,10S,12R,15R)-3-[(2R,5R,6S)-5-Ethyl-5-hydroxy-6-methyloxan-2-yl]-15-hydroxy-3,10,12-trimethyl-4,6,8-trioxadispiro[]pentadec-13-en-9-yl]-3-hydroxy-4-methyl-5-oxooctan-2-yl]-5-methyloxan-2-yl]butanoic acid soldium salt

Biological Activity for Salinomycin sodium salt

Cytotoxic to breast cancer stem cells. Inhibits CD44 expression in breast cancer cells in vitro. Inhibits mammary tumor growth in mice. Also antibiotic.

Technical Data for Salinomycin sodium salt

M. Wt 772.98
Formula C42H69NaO11
Storage Store at +4°C
CAS Number 55721-31-8
PubChem ID 45479870GC
Smiles C[C@@H]1[C@@]([C@@H](C)[C@H](O)[C@H](C)C([C@H](CC)[C@]2([H])[C@@H](C)C[C@@H](C)[C@]3(O[C@@]4(CC[C@]([C@@]5([H])CC[C@@](CC)(O)[C@H](C)O5)(C)O4)[C@H](O)C=C3)O2)=O)([H])O[C@]([C@@H](CC)C([O-])=O)([H])CC1.[Na+]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Salinomycin sodium salt

References for Salinomycin sodium salt

References are publications that support the biological activity of the product.

Gupta et al (2009) Identification of selective inhibitors of cancer stem cells by high-throughput screening. Cell 138 645 PMID: 19682730

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Citations for Salinomycin sodium salt

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