Salinomycin sodium salt

Discontinued Product

Salinomycin sodium salt (Cat. No. 3637) has been withdrawn from sale for commercial reasons.
Cat.No. 3637 - Salinomycin sodium salt | C42H69NaO11 | CAS No. 55721-31-8
Description: Antibiotic; also selectively inhibits cancer stem cells
Chemical Name: (2R)-2-[(2R,5S,6R)-6-[(3S,5S,7R,9S,10S,12R,15R)-3-[(2R,5R,6S)-5-Ethyl-5-hydroxy-6-methyloxan-2-yl]-15-hydroxy-3,10,12-trimethyl-4,6,8-trioxadispiro[4.1.5.3]pentadec-13-en-9-yl]-3-hydroxy-4-methyl-5-oxooctan-2-yl]-5-methyloxan-2-yl]butanoic acid soldium salt
Datasheet
Citations
Reviews
Literature (1)

Biological Activity

Cytotoxic to breast cancer stem cells. Inhibits CD44 expression in breast cancer cells in vitro. Inhibits mammary tumor growth in mice. Also antibiotic.

Technical Data

M. Wt 772.98
Formula C42H69NaO11
Storage Store at +4°C
CAS Number 55721-31-8
PubChem ID 45479870GC
InChI Key GCVPRXBFNOZQIX-MMUBVBEESA-M
Smiles C[C@@H]1[C@@]([C@@H](C)[C@H](O)[C@H](C)C([C@H](CC)[C@]2([H])[C@@H](C)C[C@@H](C)[C@]3(O[C@@]4(CC[C@]([C@@]5([H])CC[C@@](CC)(O)[C@H](C)O5)(C)O4)[C@H](O)C=C3)O2)=O)([H])O[C@]([C@@H](CC)C([O-])=O)([H])CC1.[Na+]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References

References are publications that support the biological activity of the product.

Gupta et al (2009) Identification of selective inhibitors of cancer stem cells by high-throughput screening. Cell 138 645 PMID: 19682730

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New Product Guide [Spring/Summer 2019]

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