SA 47

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Cat.No. 4785 - SA 47 | C17H26N4O3 | CAS No. 792236-07-8
Description: Selective FAAH inhibitor
Chemical Name: N-[2-[1-(6-Methyl-2-pyridinyl)-4-piperidinyl]ethyl]carbamic acid 2-(methylamino)-2-oxoethyl ester
Purity: ≥99% (HPLC)
Datasheet
Citations
Reviews
Literature

Biological Activity

Selective inhibitor of fatty acid amide hydrolase (FAAH). Exhibits greater selectivity for FAAH than URB 597 against multiple carboxylesterases.

Compound Libraries

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Technical Data

M. Wt 334.41
Formula C17H26N4O3
Storage Store at -20°C
Purity ≥99% (HPLC)
CAS Number 792236-07-8
PubChem ID 9840648
InChI Key HSYCMGWPPRTNKH-UHFFFAOYSA-N
Smiles CC1=CC=CC(N2CCC(CCNC(OCC(NC)=O)=O)CC2)=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 33.44 100
1eq. HCl 16.72 50

Preparing Stock Solutions

The following data is based on the product molecular weight 334.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.99 mL 14.95 mL 29.9 mL
5 mM 0.6 mL 2.99 mL 5.98 mL
10 mM 0.3 mL 1.5 mL 2.99 mL
50 mM 0.06 mL 0.3 mL 0.6 mL

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References

References are publications that support the biological activity of the product.

Zhang et al (2007) Fatty acid amide hydrolase inhibitors display broad selectivity and inhibit multiple carboxylesterases as off-targets. Neuropharmacology 52 1095 PMID: 17217969

Ahn et al (2009) Fatty acid amide hydrolase as a potential therapeutic target for the treatment of pain and CNS disorders. Expert Opin.Drug Discov. 4 763 PMID: 20544003


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Citations for SA 47

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