SA 47
Biological Activity
Selective inhibitor of fatty acid amide hydrolase (FAAH). Exhibits greater selectivity for FAAH than URB 597 against multiple carboxylesterases.
Compound Libraries
SA 47 is also offered as part of the Tocriscreen Plus. Find out more about compound libraries available from Tocris.
Technical Data
| M. Wt | 334.41 |
| Formula | C17H26N4O3 |
| Storage | Store at -20°C |
| Purity | ≥99% (HPLC) |
| CAS Number | 792236-07-8 |
| PubChem ID | 9840648 |
| InChI Key | HSYCMGWPPRTNKH-UHFFFAOYSA-N |
| Smiles | CC1=CC=CC(N2CCC(CCNC(OCC(NC)=O)=O)CC2)=N1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 33.44 | 100 | |
| 1eq. HCl | 16.72 | 50 |
Preparing Stock Solutions
The following data is based on the product molecular weight 334.41. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.99 mL | 14.95 mL | 29.9 mL |
| 5 mM | 0.6 mL | 2.99 mL | 5.98 mL |
| 10 mM | 0.3 mL | 1.5 mL | 2.99 mL |
| 50 mM | 0.06 mL | 0.3 mL | 0.6 mL |
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Product Datasheets
References
References are publications that support the biological activity of the product.
Zhang et al (2007) Fatty acid amide hydrolase inhibitors display broad selectivity and inhibit multiple carboxylesterases as off-targets. Neuropharmacology 52 1095 PMID: 17217969
Ahn et al (2009) Fatty acid amide hydrolase as a potential therapeutic target for the treatment of pain and CNS disorders. Expert Opin.Drug Discov. 4 763 PMID: 20544003
If you know of a relevant reference for SA 47, please let us know.
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Citations for SA 47
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
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