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Biological Activity for (S)-ZINC 3573
(S)-ZINC 3573 is a negative control for (R)-ZINC 3573 (Cat. No. 6351). (S)-ZINC 3573 displays no activity at MRGPRX2 at concentrations below 100 μM.
Technical Data for (S)-ZINC 3573
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for (S)-ZINC 3573
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for (S)-ZINC 3573
The following data is based on the product molecular weight 307.4. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.25 mL||16.27 mL||32.53 mL|
|5 mM||0.65 mL||3.25 mL||6.51 mL|
|10 mM||0.33 mL||1.63 mL||3.25 mL|
|50 mM||0.07 mL||0.33 mL||0.65 mL|
References for (S)-ZINC 3573
References are publications that support the biological activity of the product.
Lansu et al (2017) In silico design of novel probes for the atypical opioid receptor MRGPRX2. Nat.Chem.Biol. 13 529 PMID: 28288109
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Citations for (S)-ZINC 3573
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.