(S)-Timolol maleate

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Cat.No. 0649 - (S)-Timolol maleate | C13H24N4O3S.C4H4O4 | CAS No. 26921-17-5
Description: β1 antagonist
Chemical Name: (S)-1-[(1,1-Dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-2-propanol maleate

Biological Activity

β1-adrenergic blocker.

Technical Data

M. Wt 432.49
Formula C13H24N4O3S.C4H4O4
Storage Store at RT
CAS Number 26921-17-5
PubChem ID 5281056
Smiles [H]OC(=O)\C=C/C(=O)O[H].CC(C)(C)NC[C@H](O)COC1=NSN=C1N1CCOCC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 100 mM in water

Preparing Stock Solutions

The following data is based on the product molecular weight 432.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.31 mL 11.56 mL 23.12 mL
5 mM 0.46 mL 2.31 mL 4.62 mL
10 mM 0.23 mL 1.16 mL 2.31 mL
50 mM 0.05 mL 0.23 mL 0.46 mL

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Product Datasheets

Certificate of Analysis is currently unavailable
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Safety Datasheet


References are publications that support the products' biological activity.

Karhuvaara et al (1989) β-Adrenoceptor antagonist activities and binding affinities of timolol enantiomers in rat atria. J.Pharm.Pharmacol. 41 649 PMID: 2573714

Merck Index 12 9585 PMID:

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