(S)-Timolol maleate

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Cat.No. 0649 - (S)-Timolol maleate | C13H24N4O3S.C4H4O4 | CAS No. 26921-17-5
Description: β1 antagonist
Chemical Name: (S)-1-[(1,1-Dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-2-propanol maleate
Citations (1)
Literature (4)

Biological Activity

β1-adrenergic blocker.

Technical Data

M. Wt 432.49
Formula C13H24N4O3S.C4H4O4
Storage Store at RT
CAS Number 26921-17-5
PubChem ID 5281056
Smiles [H]OC(=O)\C=C/C(=O)O[H].CC(C)(C)NC[C@H](O)COC1=NSN=C1N1CCOCC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
water 100

Preparing Stock Solutions

The following data is based on the product molecular weight 432.49. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.31 mL 11.56 mL 23.12 mL
5 mM 0.46 mL 2.31 mL 4.62 mL
10 mM 0.23 mL 1.16 mL 2.31 mL
50 mM 0.05 mL 0.23 mL 0.46 mL

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Product Datasheets

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References are publications that support the biological activity of the product.

Karhuvaara et al (1989) β-Adrenoceptor antagonist activities and binding affinities of tim. enantiomers in rat atria. J.Pharm.Pharmacol. 41 649 PMID: 2573714

Merck Index 12 9585

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1 Citation for (S)-Timolol maleate

Citations are publications that use Tocris products. Selected citations for (S)-Timolol maleate include:

Xiao et al (2019) Acute tobacco smoke exposure exacerbates the inflammatory response to corneal wounds in mice via the sympathetic nervous system. Commun Biol 2 33 PMID: 30701198

Do you know of a great paper that uses (S)-Timolol maleate from Tocris? Please let us know.

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Literature in this Area

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