(S)-Methylisothiourea sulfate

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Cat.No. 0776 - (S)-Methylisothiourea sulfate | C4H14N4O4S3 | CAS No. 867-44-7
Description: Highly selective iNOS inhibitor
Alternative Names: SMT

Biological Activity

Highly selective, potent competitive inhibitor of iNOS.

Technical Data

M. Wt 278.36
Formula C4H14N4O4S3
Storage Store at RT
CAS Number 867-44-7
PubChem ID 13347
Smiles NC(SC)=[NH2+].NC(SC)=[NH2+].[O-]S([O-])(=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble in water

Preparing Stock Solutions

The following data is based on the product molecular weight 278.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.59 mL 17.96 mL 35.92 mL
5 mM 0.72 mL 3.59 mL 7.18 mL
10 mM 0.36 mL 1.8 mL 3.59 mL
50 mM 0.07 mL 0.36 mL 0.72 mL

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Product Datasheets

Safety Datasheet


References are publications that support the products' biological activity.

Iuvone et al (1997) Differential effect of L-NAME and S-methyl-isothiourea on leukocyte emigration in carrageenin-soaked sponge implants in rat. Br.J.Pharmacol. 121 1637 PMID: 9283697

Southan et al (1995) Isothioureas - potent inhibitors of nitric oxide synthases with variable isoform selectivity. Br.J.Pharmacol. 114 510 PMID: 7533622

If you know of a relevant reference for (S)-Methylisothiourea sulfate, please let us know.

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Keywords: (S)-Methylisothiourea sulfate, supplier, selective, iNOS, inhibitors, inhibits, Nitric, Oxide, Signaling, Signalling, Inducible, NO, Synthases, SMT, iNOS, iNOS, Tocris Bioscience

Citations for (S)-Methylisothiourea sulfate

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