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Biological Activity for (S)-(+)-Ibuprofen
(S)-(+)-Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase 1 and cyclooxygenase 2 (IC50 values are 12 and 80 μM respectively). Active isomer of ibuprofen.
Compound Libraries for (S)-(+)-Ibuprofen
Technical Data for (S)-(+)-Ibuprofen
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for (S)-(+)-Ibuprofen
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for (S)-(+)-Ibuprofen
The following data is based on the product molecular weight 206.28. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||4.85 mL||24.24 mL||48.48 mL|
|5 mM||0.97 mL||4.85 mL||9.7 mL|
|10 mM||0.48 mL||2.42 mL||4.85 mL|
|50 mM||0.1 mL||0.48 mL||0.97 mL|
Product Datasheets for (S)-(+)-Ibuprofen
References for (S)-(+)-Ibuprofen
References are publications that support the biological activity of the product.
Kato et al (2001) Cyclooxygenase-1 and cyclooxygenase-2 selectivity of non-steroidal anti-inflammatory drugs: investigation using human peripheral monocytes. J.Pharm.Pharmacol. 53 1679 PMID: 11804398
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Keywords: (S)-(+)-Ibuprofen, (S)-(+)-Ibuprofen supplier, Cyclooxygenase, inhibitors, inhibits, COX-1, COX-2, Oxygenases, Oxidases, 2796, Tocris Bioscience
Citations for (S)-(+)-Ibuprofen
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Alzheimer's disease (AD) is a degenerative brain disease and the most common cause of dementia, affecting approximately 47 million people worldwide. Updated in 2015, this poster summarizes the structural and functional changes observed in the progression of this neurodegenerative disease, as well as classic AD drug targets.
Epilepsy is a brain disease that affects 60 million people globally. More than 20 anti-seizure drugs are currently available, but these do not address the underlying causes of the condition. This poster summarizes current knowledge about the development of the condition and highlights some approaches that have disease-modifying effects in proof-of-concept studies.
Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.