(S)-(+)-α-Methylhistamine dihydrobromide

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Cat.No. 0572 - (S)-(+)-alpha-Methylhistamine dihydrobromide | C6H11N3.2HBr | CAS No. 75614-93-6
Description: H3 agonist, less active enantiomer
Chemical Name: (S)-(+)-α-Methyl-1H-imidazole-4-ethanamine dihydrobromide

Biological Activity

Less active enantiomer of H3 agonist R-(-)-α-methylhistamine; 120-fold less potent than R-(-) at H3.

R-enantiomer also available.

Technical Data

M. Wt 287
Formula C6H11N3.2HBr
Storage Desiccate at RT
CAS Number 75614-93-6
PubChem ID 45073439
Smiles N[C@@H](C)CC1=CNC=N1.Br.Br

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 100 mM in water

Preparing Stock Solutions

The following data is based on the product molecular weight 287. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.48 mL 17.42 mL 34.84 mL
5 mM 0.7 mL 3.48 mL 6.97 mL
10 mM 0.35 mL 1.74 mL 3.48 mL
50 mM 0.07 mL 0.35 mL 0.7 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet


References are publications that support the products' biological activity.

Hill (1990) Distribution, properties and functional characteristics of three classes of histamine receptor. Pharmacol.Rev. 42 45 PMID: 2164693

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Citations for (S)-(+)-α-Methylhistamine dihydrobromide

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