(S)-5-Bromowillardiine

Discontinued Product

(S)-5-Bromowillardiine (Cat. No. 0304) has been withdrawn from sale for commercial reasons.
Cat.No. 0304 - (S)-5-Bromowillardiine | CAS No. 19772-78-2
Description: Active isomer of (0132)
Chemical Name: (S)-(-)-a-Amino-5-bromo-3,4-dihydro-2,4-dioxo-1(2H)pyridinepropanoic acid
Datasheet
Citations
Reviews
Literature

Biological Activity

Potent AMPA receptor agonist. Also active at dorsal root C fibre kainate receptors and DRG cells.

Technical Data

M. Wt 278.06
Storage Store at RT
CAS Number 19772-78-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Product Datasheets

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References

References are publications that support the biological activity of the product.

Hawkins et al (1995) Binding of the new radioligand (S)-[3H]-AMPA to rat synaptic membranes: effects of a series of structural analogues of the non-NMDA receptor agonist willardine. Neuropharmacology 34 405 PMID: 7566471

Patneau et al (1992) Activation and desensitization of AMPA/kainate receptors by novel derivatives of willardiine. J.Neurosci. 12 595 PMID: 1371315

Jane et al (1991) New willardiine analogues with potent stereoselective actions of mammalian spinal neurones. Br.J.Pharmacol. 104 333P

Thompson et al (1996) Depolarising effects of certain derivatives of (S)-willardine upon in vitro neonatalrat dorsal roots. Br.J.Pharmacol. 117 331P

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Keywords: (S)-5-Bromowillardiine, (S)-5-Bromowillardiine supplier, AMPA, Receptors, 0304, Tocris Bioscience

Citations for (S)-5-Bromowillardiine

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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

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