(S)-3-Hydroxyphenylglycine

Pricing Availability Delivery Time Qty
Cat.No. 0326 - (S)-3-Hydroxyphenylglycine | C8H9NO3 | CAS No. 71301-82-1
Description: Group I mGlu agonist, active isomer
Alternative Names: (S)-3H-PG
Purity: ≥99% (HPLC)
Datasheet
Citations
Literature

Biological Activity

Agonist at group I metabotropic glutamate receptors (mGlu1) having no effect at mGlu2 or mGlu4. (RS)-3-Hydroxyphenylglycine (Cat. No. 0324) also available.

Technical Data

M. Wt 167.16
Formula C8H9NO3
Storage Desiccate at RT
Purity ≥99% (HPLC)
CAS Number 71301-82-1
PubChem ID 6604712
InChI Key DQLYTFPAEVJTFM-ZETCQYMHSA-N
Smiles OC1=CC=CC([C@@](N)([H])C(O)=O)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
1eq. HCl 16.72 100
1eq. NaOH 16.72 100
water 8.36 50
phosphate buffered saline 8.36 50

Preparing Stock Solutions

The following data is based on the product molecular weight 167.16. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 5.98 mL 29.91 mL 59.82 mL
5 mM 1.2 mL 5.98 mL 11.96 mL
10 mM 0.6 mL 2.99 mL 5.98 mL
50 mM 0.12 mL 0.6 mL 1.2 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Birse et al (1993) Phenylglycine derivatives as new pharmacological tools for investigating the role of metabotropic glutamate receptors in the central nervous system. Neuroscience 52 481 PMID: 7680790

Hayashi et al (1994) Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes. J.Neurosci. 14 3370 PMID: 8182479


If you know of a relevant reference for (S)-3-Hydroxyphenylglycine, please let us know.

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View all Glutamate (Metabotropic) Group I Receptor Agonists

Keywords: (S)-3-Hydroxyphenylglycine, supplier, Group, I, mGlur, agonists, active, isomer, Receptors, mGlu1, mGlu5, mGluR1, mGluR5, Glutamate, Metabotropic, (S)-3H-PG, Glutamate, (Metabotropic), Group, I, Receptors, Glutamate, (Metabotropic), Group, I, Receptors, Tocris Bioscience

Citations for (S)-3-Hydroxyphenylglycine

Citations are publications that use Tocris products.

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